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Research supports the use of the anticonvulsants gabapentin (Gralise, Neurontin, Horizant) and pregabalin (Lyrica) to help relieve pain caused by damaged nerves. Both gabapentin and pregabalin are particularly effective in the treatment of postherpetic neuralgia, diabetic neuropathy and pain caused by a spinal cord injury. Neurontin Alternatives Compared. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Neurontin (gabapentin) Gabapentin is a common prescription for sciatica, but the evidence supporting its use is weak. Learn about other medications that may help, such as diclofenac, prednisone, pregabalin, and amitriptyline. Tramadol: Tramadol works on the central nervous system and can be an alternative to gabapentin for managing moderate to severe pain. Over-the-counter (OTC) options. OTC alternatives to gabapentin may help manage mild to moderate pain and anxiety. However, nonprescription options typically aren’t as effective at treating these conditions. Your doctor will be able to determine the best medication for your specific health needs. If gabapentin does not work for you, or if you believe the side effects are too severe, talk with your doctor to find an alternative medicine to treat nerve pain and/or seizures. Antidepressants. Certain antidepressants work to relieve pain. Drugs like gabapentin and pregabalin, Neurontin, and Lyrica bind these receptors at the alpha-2-delta subunit of the Cav2.2 channel, reducing pain signal transmission. This class of medications is called gabapentinoids, and while these medications are now widely used for nerve pain and epilepsy, as they are the best we have right now, they are We would like to show you a description here but the site won’t allow us. Gabapentin has an average rating of 7.2 out of 10 from a total of 2570 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 21% reported a negative effect. Caplyta has an average rating of 6.6 out of 10 from a total of 183 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 29% reported a negative effect. Learn about the benefits and side effects of gabapentin, a drug used for epilepsy and nerve pain. Find out four gabapentin alternatives, including other drugs and natural remedies, that may help you manage your condition. The web page reviews a study that compared four medications for idiopathic sensory polyneuropathy, a condition of unknown cause that damages nerves. It concludes that none of the medications was very effective or safe, and suggests more research is needed. Finding effective alternatives to Gabapentin involves exploring various avenues such as herbal remedies, dietary adjustments, lifestyle changes, nutritional supplements, acupuncture therapy—and more! Neurontin: Gabapentin · Oral capsule: 100 mg, 300 mg, 400 mg · Oral tablet: 600 mg, 800 mg · Oral solution: 50 milligrams per milliliter (mg/mL) Gralise: Gabapentin · Oral tablet: 300 mg, 600 mg: Horizant: Gabapentin enacarbil · ER tablet: 300 mg, 600 mg: Lyrica: Pregabalin Pregabalin and gabapentin both resulted in moderate to large increases in cognitive effects (4.8%), dizziness (25.6%), and weight gain (10.1%); pregabalin also resulted in large increases in the Learn about different types of drugs that can help with neuropathic pain, such as antidepressants and anticonvulsants. Gabapentin is one of the anticonvulsants that can reduce pain signals in the nerves, but it may have side effects. Gabapentin is a medication primarily used to treat neuropathic pain and seizures. For many, it has been a lifesaver, providing relief where other treatments have failed. However, some individuals may experience side effects or find that Gabapentin isn’t effective for them. In such cases, exploring alternatives can be beneficial. Alternatives to Gabapentin. It’s important to explore options under the guidance of a healthcare provider. Here are some alternatives to gabapentin that may be considered: Prescription Medications. Pregabalin (Lyrica): Similar to gabapentin, pregabalin is an anticonvulsant frequently prescribed for neuropathic pain. Anti-epileptic drugs, especially ones like gabapentin (Neurontin) and pregabalin (Lyrica), can help treat persistent nerve pain from the following conditions: Diabetes. Shingles. Spinal cord injury. Fibromyalgia. In general, these medications work by calming down neurons (nerve cells). Alternatives to gabapentin exist for similar conditions, and a healthcare professional can determine the most appropriate option based on individual needs. Summary of key points about gabapentin. Gabapentin is an anticonvulsant medication commonly used to treat seizures, nerve pain, and other conditions.
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