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This list is not complete and many other drugs may affect gabapentin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. There are a number of drugs that should not be taken with gabapentin, including certain antibiotics, antifungal medications, and drugs used to treat seizures. In some cases, taking these drugs with gabapentin can increase the risk of side effects or make the gabapentin less effective. There are 4 disease interactions with gabapentin. Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Always talk to your prescriber or pharmacist before taking gabapentin; they can check for interactions with other medications and substances. To limit tiredness from gabapentin, work with your prescriber to find the lowest dose that works for you. And if your tiredness doesn’t improve or is affecting your daily life, let them know. 3. Find patient medical information for Gabapentin (Gralise, Neurontin) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Gabapentin should not be mixed with any other illicit drugs, alcohol, or certain prescription medications like hydrocodone and morphine. If you’re considering taking an over-the-counter medication while on gabapentin, discuss it with your doctor before making a decision. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Gabapentin drug interactions. There are 270 drug interactions with gabapentin. Gabapentin disease interactions. There are 4 disease interactions with gabapentin which include: drug dependence; renal dysfunction; suicidal tendency; hemodialysis Gabapentin, a medication primarily used to treat seizures and nerve pain, is generally considered safe when used as directed. However, like many medications, it can interact negatively with other substances, leading to unwanted side effects or reduced efficacy. These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate Are there any serious interactions with gabapentin and other medications? Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Some examples include narcotic opioids, anti-anxiety medicines, antidepressants, and antihistamines. Below are common gabapentin interactions and their associated effects: Losartan (angiotensin II receptor blocker): The combination of gabapentin and losartan may increase the risk of dizziness and drowsiness. Ethacrynic acid (diuretic): Gabapentin may decrease the effectiveness of ethacrynic acid. Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Drug Interactions between gabapentin and tramadol. This report displays the potential drug interactions for the following 2 drugs: gabapentin; tramadol; Edit list (add/remove drugs) Consumer; Professional; Interactions between your drugs Gabapentin, often prescribed for nerve pain, seizures, and other conditions, can interact with a range of other medications, sometimes leading to adverse effects. It’s essential to be aware of these potential interactions to ensure safe and effective treatment. Gabapentin enacarbil (brand name Horizant) is a prodrug of gabapentin that has been designed to overcome the limitations of gabapentin, such as poor absorption and a short duration of action. It requires hydrolyzation in the gastrointestinal tract to become active. Gabapentin belongs to the group of medicines known as anticonvulsants. 2. Upsides Gabapentin may interact with certain medications or supplements. Because of drug interactions, using gabapentin with certain medicines is typically not recommended, but may be required in some cases.
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