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The opioid epidemic in America is real and is estimated to be the number one cause of death in adults under 50 years of age. Finding alternative analgesic medications is part of the effort to decrease the prescription of narcotics, with gabapentin Misusing gabapentin can lead to a fatal overdose, though the risk is much less if you take it as prescribed. However, unlike opioids, there is no antidote to reverse the overdose like naloxone. A gabapentin overdose is a medical emergency. Gabapentin-involved overdose deaths doubled in Q2 2020 compared to Q1 2019, the CDC reports. What do you know, and maybe not know, about the troubling trend? Symptoms of Gabapentin Overdose. Most side effects of a gabapentin overdose will be related to an overall deceleration of the body’s systems. Drowsiness, muscle weakness, lethargy and drooping eyelids can be expected. Other gabapentin overdose symptoms include diarrhea and sedation. Can You Overdose on Gabapentin? Although it’s possible to overdose on gabapentin, it’s relatively non-lethal. However, it can become dangerous when abused with other substances. 2. Mixing gabapentin with other substances, like alcohol or opioids, can amplify their side effects. Of these overdose deaths, 5,687 (9.7%) had gabapentin detected in postmortem toxicology, and of those deaths, gabapentin was determined to be the cause of death in 49% of people at the beginning of 2019, with an increase to 55% by the end of 2020. This report also collected information on concomitant medication use. Gabapentin overdose can be serious and may result in many symptoms, from mild drowsiness to life-threatening complications. Understanding the signs, risks, and proper management of gabapentin overdose is crucial for medical professionals and individuals using the medication. Routine gabapentin testing, as part of comprehensive postmortem toxicology testing protocols for drug overdose death investigations, could further elucidate its role in drug overdose deaths. Despite the lack of uniform testing, gabapentin detection and involvement in overdose deaths increased during 2019–2020. Postmortem toxicology tests detected gabapentin in almost 1 in 10 US overdose deaths between 2019 and 2020. In about half of the cases, a medical examiner or coroner ruled the drug was a cause of the death, according to a report from the CDC’s Division of Overdose Prevention. Between 2019 and 2020, gabapentin was implicated in one in 10 US overdose deaths. Gabapentin overdose can be successfully treated with prompt medical attention. Though gabapentin has risks, stopping gabapentin use abruptly can lead to serious withdrawal symptoms. Only 19 deaths involving gabapentin were identified as possible suicides during the five-year study period, but there were thousands of gabapentin-related calls each year coded as attempted suicides — including over 10,000 calls in 2017 alone. In cases in which gabapentin was determined to be a cause of death, the blood concentrations ranged from 1.1 to 134.0 mg/L. Persons who died of a gabapentin-related drug death were prescribed the drug legitimately 91.4% of the time, with 84.2% of those also having a known prior history of abuse or misuse of prescription medications. Common symptoms of gabapentin overdose are drowsiness, fast heartbeat, dizziness, low blood pressure, nausea, vomiting, and impaired coordination. In severe cases, lethargy, coma, and death may occur. Most gabapentin-involved overdose deaths, 83.2%, occurred among non-Hispanic White persons. More than half of gabapentin-involved deaths, 52.2%, occurred among persons aged 35 to 54 years. Individuals who died from a gabapentin-related overdose were most likely to be non-Hispanic white (83%), between the ages of 35 and 54 years (52%), with men and women equally affected. Deaths hit a peak in the second quarter of 2020, but remained high through the rest of the study period. on death certificates by some certifiers; therefore, overdose . deaths involving gabapentin or with gabapentin detected are likely underestimated. Routine gabapentin testing, as part of comprehensive postmortem toxicology testing protocols for drug overdose death investigations, could further elucidate its role in drug overdose deaths. Individuals who overdose on a combination of gabapentin and other drugs with depressant effects are at a higher risk of death and should receive medical attention immediately. If you notice that a loved one is exhibiting any signs of a gabapentin overdose, go to the emergency room or call 9-1-1 immediately. Gabapentin is an antiepileptic drug that is prescribed for both FDA-approved and multiple off-label conditions, and has a relatively safe side-effect profile. Rare cases of overdose-related adverse effects have been reported in the literature. Described herein are the circumstances and autopsy findi Signs and Symptoms of Gabapentin Overdose. A gabapentin overdose can be dangerous or even deadly. Some factors can increase the risk of a fatal overdose, such as taking several substances at once. Gabapentin overdose symptoms can include: Drowsiness; Movement difficulties; Dizziness; Nausea or vomiting; Rapid heartbeat; Low blood pressure When Gabapentin is either mixed with opioids or alcohol, it can cause individuals misusing the drugs to overdose, and even risk death from the Gabapentin itself. Opioid overdose can often be reversed by administering naloxone, which many states have made available to purchase over the counter. Emergency services must still be contacted immediately.
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