Horizant (gabapentin enacarbil) is used to treat restless legs syndrome and nerve pain caused by the herpes virus. Includes Horizant side effects, interactions and indications. Gabapentin enacarbil (Horizant (ER) (U.S.), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. Gabapentin enacarbil is used to treat moderate-to-severe primary Restless Legs Syndrome (RLS). RLS is a neurologic disorder that makes the legs feel uncomfortable. This results in an irresistible feeling of wanting to move your legs to make them comfortable. Gabapentin enacarbil is a gabapentin prodrug used to treat Restless Legs This compound belongs to the class of organic compounds known as gamma amino acids and Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] More about Gabapentin: More about Gabapentin enacarbil: Ratings & Reviews: Gabapentin has an average rating of 7.2 out of 10 from a total of 2568 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 21% reported a negative effect. Gabapentin enacarbil is classified as a BCS Class 2 compound (low solubility, high permeability). The applicant provided adequate information regarding structure elucidation and What Is Gabapentin Enacarbil and How Does It Work? Gabapentin Enacarbil is a prescription medication used for treating the symptoms of restless leg syndrome and postherpetic neuralgia . Gabapentin Enacarbil is available under the following different brand names: Horizant Gabapentin enacarbil: Commercially available as extended-release tablets (Horizant). Because of differences in pharmacokinetics that affect frequency of administration, gabapentin enacarbil extended-release tablets are not interchangeable with other gabapentin preparations. (See Pharmacokinetics.) Horizant (gabapentin enacarbil) is commonly used to treat the following conditions. Horizant may also be used for other conditions as determined by your healthcare provider. How does Horizant Two agents from this class, pregabalin (Sommer et al., 2007) and gabapentin enacarbil (Kushida et al., 2009), are under investigation as treatments for RLS. Pregabalin is a gabapentin analog and is virtually identical to it in terms of its mechanism of action therapeutic profile ( Sills, 2006 ). Gabapentin enacarbil is marketed under the name Horizant. It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). Therapeutic Class: Analgesic. Pharmacologic Class: Gabapentinoid. Chemical Class: Gamma Aminobutyric Acid (class) Important Safety Information for HORIZANT® (gabapentin enacarbil) Extended-Release Tablets INDICATIONS. HORIZANT® (gabapentin enacarbil) is a prescription medicine used to: treat adults with moderate to severe primary Restless Legs Syndrome (RLS). Horizant (gabapentin enacarbil) is FDA-approved to treat restless leg syndrome (RLS) and nerve pain from shingles in adults. This medication belongs to the drug class called antiepileptics. Horizant (gabapentin enacarbil) is an extended-release tablet that's taken by mouth. HORIZANT® (gabapentin enacarbil) Extended-Release Tablets are indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS) in adults. HORIZANT is not recommended for patients who are required to sleep during the daytime and remain awake at night. HORIZANT® (gabapentin enacarbil) Extended-Release Tablets are indicated for the management of postherpetic neuralgia (PHN Drug class: gamma-aminobutyric acid analogs; Patient resources. Gabapentin enacarbil side effects can vary depending on the individual. Always consult your Horizant® is the only medication in its class that is FDA approved to treat RLS. 5-7 Learn more about this once-daily treatment option (gabapentin enacarbil) is Gabapentin enacarbil is a prodrug of gabapentin, an antiepileptic drug (AED); AEDs increase risk of suicidal thoughts or behavior in patients taking these drugs for any indication; because gabapentin enacarbil is a prodrug of gabapentin, it also increases this risk Horizant (gabapentin enacarbil) is an extended release tablet used to treat restless legs syndrome and for the pain from having shingles (postherpetic nerve pain). Generic brands of gabapentin capsules, USP are used for postherpetic nerve pain and for add on therapy for partial onset seizures in patients 3 years and older
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