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For me, Cymbalta replaced Nortriptyline, a few years ago. I saw an article last week indicating that it has become the most trustworthy medication for neuropathy pain and the anxiety it creates for all of us. I have worked up to 60 mg every day in the morning. That’s the situation for millions of people who suffer from idiopathic sensory polyneuropathy. The term “idiopathic” means that no cause can be identified; “sensory” refers to the type of nerve, in this case those carrying nerve signals such as pain or temperature; “poly” means “many” and “neuropathy” means nerve disease. Its FDA-approved indications include the treatment of partial seizures and neuropathic pain associated with conditions including postherpetic neuralgia (pain following shingles). Off label, gabapentin is commonly used for anxiety, fibromyalgia, and chronic pain management. Cymbalta is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Cymbalta is also used in adults to treat nerve pain caused by diabetes (diabetic neuropathy), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain). We compare the side effects and drug effectiveness of Gabapentin and Cymbalta. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 612,354 people who take Gabapentin and Cymbalta, and is updated regularly. Both gabapentin and Cymbalta can be effective in reducing nerve pain, but their effectiveness varies among individuals and specific pain conditions. Some people respond better to one medication over the other. The results showed that, at the end of the study, duloxetine was significantly superior to gabapentin in terms of the incidence of adverse reactions (RR = 0.59, 95% CI: 0.45–0.79, P < 0.01), sleep interference score (SMD = −0.35, 95% CI: −0.63 to −0.08, P < 0.05), but no significant differences in VAS score (SMD = −0.14, 95% CI: −0.31–0.03, P > It works well for managing severe pain and I have better mobility. I have Syringomyelia as well as Fibromyalgia. However, I still have terrible stiffness and fatigue. My PCP wants me to try adding Cymbalta and then eventually it will replace Gabapentin. Gralise (gabapentin) and Cymbalta (duloxetine) are used to treat different types of neuralgia (nerve pain). Gabapentin is used postherpetic neuralgia from herpes zoster (nerve damage from shingles) and to treat seizure disorders. Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may Examples of SNRIs include duloxetine (Cymbalta) and venlafaxine (Effexor), which can help treat neuropathic pain. However, these drugs can result in side effects. Duloxetine can cause: The This systematic review and meta-analysis of randomized controlled trials assessed the efficacy and safety of gabapentin and duloxetine for treating patients with painful diabetic peripheral Cymbalta is also used to relieve the symptoms of fibromyalgia, a chronic pain disorder characterized by widespread pain, fatigue, and tenderness in certain areas of the body.In addition, Cymbalta is prescribed for peripheral neuropathy, a condition that causes nerve damage, resulting in numbness, tingling, and pain usually in the hands and feet. For most individuals, it is safe to take gabapentin and Cymbalta (duloxetine) together. In fact, they are commonly used in combination to treat certain conditions, like neuropathy (nerve-type pain). There are some precautions, that I list below, but generally, they are of low risk. Nerve pain medication: Gabapentin (Neurontin) and pregabalin (Lyrica) may help reduce neck and back nerve pain, especially sciatica. Begin with low doses to avoid daytime drowsiness and fall risk. Muscle relaxants. Tizanidine (Zanaflex) and baclofen (Lioresal) may reduce pain from muscle spasms. Nerve damage from diabetes that leads to tingling, numbness, burning, or pain, usually in the legs and feet (diabetic peripheral neuropathy) Long-term condition that involves sleep problems
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