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In this section, we will explore the mechanism by which gabapentin can lead to edema. Gabapentin is an anticonvulsant medication commonly prescribed for managing various neurological conditions such as epilepsy and neuropathic pain. While gabapentin is generally well-tolerated, some individuals may experience edema as a side effect. This drug can also act as a pain reliever for various conditions that affect the nervous system, Gabapentin can cause some rare but serious side effects. swelling in the legs or feet from This study helps us to admit the point that switching brand of gabapentin could cause new side-effects. It is necessary that the physicians know the side-effects of drugs such as gabapentin and notice that an anti-analgesic drug can cause pain too. Distinguish of drug side-effects can prevent of lab tests of unnecessary. I have swelling in my legs caused by lymphedema and have to wear compression socks but mine was not caused by a medication. I also would be concerned if it's been over 5 months since stopping gabapentin and the swelling and pain is still in the hands and feet. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Has anyone ever had the experience of Gabapentin causing severe muscle cramps in arms and legs and muscular pain and feeling of weakness? I know it is supposed to basically do the opposite and help with muscular problemsbut this has happened twice to me as soon as I started the gaba and it was very severe, You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Related studies Foot, leg, and ankle swelling in Gabapentin; How the study uses the data? The study is based on gabapentin (the active ingredients of Gabapentin). Other drugs that have the same active ingredients (e.g Gabapentin, a medication primarily known for its use in treating seizures and nerve pain, has a complex relationship with the legs. While not specifically designed to target leg issues, gabapentin’s mechanisms of action and side effects can significantly impact this part of the body. Gabapentin is fairly safe when you use it correctly. It does come with some possible side effects, though. People who misuse this drug are also at risk of additional side effects. Although the mechanism behind peripheral edema from gabapentin is largely unknown, it has been theorized to be similar to the mechanism in which other calcium channel blockers (eg, amlodipine) cause peripheral edema.6,7 This relationship has been hypothesized to be due to gabapentin's actions on presynaptic voltage-gated calcium channels.1,6,7 Sorry to say, but my swelling lead to weight gain. I was prescribed Gabapentin for nerve pain. I started at 200 mgs once daily at bedtime. I couldn't stay on it for longer than two weeks. I became agitated and restless. I couldn't sleep.It didn't help my nerve pain at all. It may work for you. Amlodipine (Norvasc), gabapentin (Neurontin, Horizant, Gralise), and pregabalin (Lyrica) can cause puffy legs and ankles. Birth control pills, certain over-the-counter pain medications, and steroids are a few other culprits. This case illustrates that lower doses of gabapentin can also cause this adverse effect. It is important to recognize this adverse effect because gabapentin is used in conditions like diabetic neuropathy, which is associated with multiple co-morbidities that can give rise to bilateral leg swelling. Presence of gabapentin induced leg swelling I get swelling below the knee, closer to my ankle. I just wear socks that have a loose neck or just roll them down below the swelling. Swollen arms and legs Gabapentin is a common medication-related cause of peripheral edema . This is when you experience swollen tissues in the body, often in the arms and legs. Gabapentin can cause changes in kidney function or fluid balance in the body. When the body retains excess fluid, it can lead to noticeable swelling in areas like the legs, ankles, or hands. Allergic Reactions swelling of the face and throat, a condition called angioedema; problems speaking or swallowing; changes in memory, ability to concentrate, or personality. Gabapentin may cause breathing problems in people who use opioid pain medicines and those with chronic obstructive pulmonary disease (COPD). Although the mechanism behind peripheral edema from gabapentin is largely unknown, it has been theorized to be similar to the mechanism in which other calcium channel blockers (eg, amlodipine) cause peripheral edema. 6,7 This relationship has been hypothesized to be due to gabapentin's actions on presynaptic voltage-gated calcium channels. 1,6 Patients taking Neurontin may experience swelling in the feet and ankles. The presence of lower leg swelling may cause discomfort and impair walking. My mother-in-law was unable to wear regular shoes because of swelling of her feet and ankles, so we found her socks and soft slippers that fit her feet comfortably. I have been on Gabapentin for 3years. The last 2 months I have had swelling in hand & feet, joint pain, as well as low back pain. I know its from the medicine because I decided to stop taking it for a week and it stopped hurting. But as soon as it was back in my system the pain & swelling returned. Any views on this would be appreciated.
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