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Lyrica may cause weight gain, but it’s not exactly known why. It may be related to the fact that Lyrica can increase your appetite. Weight gain can also occur with edema. The longer you take Lyrica, the more likely weight gain may be. It’s also more likely with higher doses (300 mg daily or more). FDA-approved drugs may cause fatigue, dizziness, brain fog and weight gain. Pregabalin (Lyrica) has become a go-to drug for nerve pain (neuropathy). There aren’t many medications in the doctor’s tool kit for this kind of problem. A similar drug, gabapentin, has been approved for treating epilepsy and postherpetic neuralgia. Lyrica is more likely than gabapentin to cause side effects such as dry mouth, constipation, swelling (edema), breast enlargement, or weight gain; Gabapentin is more likely than Lyrica to cause side effects such as difficulty speaking, fever, an increased risk of viral infections, unusual eye movements, or jerky movements Gabapentin is thought to cause weight gain by increasing patients’ appetites and causing fatigue that reduces their physical activity. It can also cause water retention, with swelling (edema) of the hands, arms, feet, and legs, which may contribute to weight gain. Related: Does Trazodone cause weight gain? One study found that in patients When comparing pregabalin versus gabapentin, they work in similar ways but pregabalin is absorbed more quickly and fully. Common side effects of both medications include dizziness, drowsiness, and fluid buildup. Pregabalin is more likely to lead to weight gain. Pregabalin is a controlled substance in every U.S. state. A review of research examining antipsychotic medicine explains why: Most of those drugs cause weight gain. Over the course of treatment, around 7 in 10 patients will gain weight — rapidly in the initial period after starting these meds, but it continues over the long term. The risk appears to be highest with: Olanzapine (Zyprexa) Clozapine Some of them can also help prevent migraines and manage nerve pain. But some anticonvulsants can cause weight gain, including: Gabapentin (Neurontin) Pregabalin (Lyrica) Carbamazepine (Tegretol, Equetro) Valproate (Depakene, Depakote) It’s not clear why medications like gabapentin cause weight gain, but it could be due to increased appetite Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Rare but serious gabapentin side effects include mood changes in children. It can also cause suicidal thoughts or behaviors in children and adults. Medications that cause weight gain: Several medications can cause weight gain. But some are more likely to do so than others. Gabapentin side effects: Weight gain is a possible gabapentin side effect, though it’s not the most common. Drowsiness, dizziness, and swelling are more likely. Does Lyrica Cause Weight Gain Like Gabapentin There is no definitive answer to this question as everyone experiences different side effects from taking lyrica. Some people may experience weight gain as a result of taking lyrica, while others may not. Very few people (around 0.3%) stop taking Lyrica due to weight gain. But it might be best to get advice from your doctor for the following situations: Substantial weight gain. Lyrica-associated weight gain can also be risky if it’s substantial. At the very least, it is known that Lyrica does tend to have a faster onset of action and doesn't require slow dose titration, as gabapentin does. In addition, Lyrica was initially thought to have less side effects than gabapentin since the drugs are so similar to one another but Lyrica is dosed in far less amounts. Yes, weight gain is one of the most common side effects with Lyrica (generic name: pregabalin) in both adults and children. In studies that were 14 weeks long in adults, 9% of Lyrica-treated patients and 2% of placebo (inactive treatment) patients gained 7% or more over their weight at the beginning of the study. Lyrica can cause certain side effects, some of which are more common than others. Both Neurontin (gabapentin) and Lyrica it’s not known what effects Lyrica weight gain may have long-term. Weight gain is not considered a common side effect of gabapentin. In clinical trials, only about 2% of people reported weight gain with its use. In people who do gain weight while on gabapentin, a research study showed a weight gain of about 5.5 pounds after 1.5 months of use. There is evidence linking Lyrica and weight gain, suggesting that 10% to 20% of users will gain weight. Since a greater percentage of Lyrica users gain weight, and Gabapentin is similar – some believe that the reports of weight gain on Gabapentin are low-ball estimates. Gabapentin may cause weight gain, but it is an uncommon side effect. Studies have shown that a small number of people taking gabapentin, a drug used to treat epilepsy and postherpetic neuralgia, experienced weight gain. People who do gain weight may gain about 5 pounds after 6 weeks of use. Pregabalin can cause both water retention and weight gain. Water retention is when the body holds onto excess fluid, leading to swelling in areas like the legs and feet. On the other hand, weight gain can occur due to increased appetite, reduced physical activity, or changes in metabolism. Does Lyrica cause weight gain? How long does Lyrica stay in your system? Cymbalta, topiramate, Neurontin, methylprednisolone, Medrol, clonazepam, lorazepam. Images. Lyrica and its popular predecessor Gabapentin (Neurontin) have both been shown to cause significant weight gain. In a 2008 study, patients taking Lyrica for epilepsy, gained approximately 4 kg (8 lb) in a 3 to 6-month period.
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