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Gabapentin enacarbil is used to treat moderate-to-severe primary Restless Legs Syndrome (RLS). RLS is a neurologic disorder that makes the legs feel uncomfortable. This results in an irresistible feeling of wanting to move your legs to make them comfortable. HORIZANT® (gabapentin enacarbil) Extended-Release Tablets are indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS) in adults. HORIZANT is not recommended for patients who are required to sleep during the daytime and remain awake at night. HORIZANT® (gabapentin enacarbil) Extended-Release Tablets are indicated for the management of postherpetic neuralgia (PHN Horizant (gabapentin enacarbil) is used to treat restless legs syndrome and nerve pain caused by the herpes virus. Includes Horizant side effects, interactions and indications. Important Safety Information for HORIZANT® (gabapentin enacarbil) Extended-Release Tablets INDICATIONS. HORIZANT® (gabapentin enacarbil) is a prescription medicine used to: treat adults with moderate to severe primary Restless Legs Syndrome (RLS). Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] Horizant (gabapentin enacarbil) is FDA-approved to treat restless leg syndrome (RLS) and nerve pain from shingles in adults. This medication belongs to the drug class called antiepileptics. Horizant (gabapentin enacarbil) is an extended-release tablet that's taken by mouth. The oral bioavailability of gabapentin enacarbil (as gabapentin) is greater than or equal to 68%, across all doses assessed (up to 2,800 mg), with a mean of approximately 75%. [25] [1] In contrast to the other gabapentinoids, the pharmacokinetics of phenibut have been little-studied, and its oral bioavailability is unknown. [28] Gabapentin Enacarbil. Generic name: Gabapentin Enacarbil [ gab-a-PEN-tin-en-a-KAR-bil ] Brand name: Horizant Drug class: Gamma-aminobutyric acid analogs. Medically reviewed by drugclasses.com. Last updated on May 5, 2024. Uses; Before taking; Warnings; Dosage; Side effects; Overdose; Uses of Gabapentin Enacarbil: It is used to treat restless Drug Interactions: A total of 270 drugs are known to interact with Gabapentin enacarbil: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) 10 minor drug interactions (52 brand and generic names) A total of 258 drugs are known to interact with Pramipexole: Horizant (gabapentin enacarbil) gabapentin enacarbil 600 mg (GS LFG) View larger images Drugs.com Mobile App Access drug & treatment information, identify pills, check interactions and set up personal medication records. Common Generic Name(s): gabapentin enacarbil; Pronunciation: GAB-a-pen-tin, ho-RI-zant; Drug Classes: GABA analog; Availability: prescription only, no generic available; How is it used? Gabapentin enacarbil extended release tablets available under the trade name Horizant and gabapentin are not interchangeable. Use: Postherpetic neuralgia. Usual Adult Dose for Restless Legs Syndrome: Gabapentin enacarbil available under the trade name Horizant: 600 mg orally once daily with food at about 5 PM Gabapentin Enacarbil is a prescription medication used for treating the symptoms of restless leg syndrome and postherpetic neuralgia. Gabapentin Enacarbil is available under the following different brand names: Horizant Gabapentin enacarbil is a gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). Gabapentin enacarbil: Commercially available as extended-release tablets (Horizant). Because of differences in pharmacokinetics that affect frequency of administration, gabapentin enacarbil extended-release tablets are not interchangeable with other gabapentin preparations. (See Pharmacokinetics.) Gabapentin enacarbil is used to treat moderate-to-severe primary Restless Legs Syndrome (RLS). RLS is a neurologic disorder that makes the legs feel uncomfortable. This results in an irresistible feeling of wanting to move your legs to make them comfortable. Horizant Dosage. Generic name: gabapentin enacarbil 300mg Dosage form: tablet, extended release Drug class: Gamma-aminobutyric acid analogs Medically reviewed by Drugs.com. Last updated on Aug 29, 2023. Released gabapentin is not appreciably metabolized in humans. Neither gabapentin enacarbil nor gabapentin are substrates, inhibitors, or inducers of the major cytochrome P450 enzymes (CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4). Gabapentin enacarbil is neither a substrate nor an inhibitor of P-glycoprotein in vitro. Gabapentin belongs to a class of drugs known as anti-seizure or anticonvulsant drugs. HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking gabapentin enacarbil and each time you get a refill. Compare Gabapentin vs Gabapentin Enacarbil head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
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