There are some reported drug interactions between Benadryl and your current medications (Effexor & gabapentin). In most people, these interactions are not a major concern and taking Benadryl to treat allergies or as a sleep aid is safe. 7 diphenhydramine interactions to know about There are many possible interactions with diphenhydramine. Below, we’ll go over some common ones to watch out for. Keep in mind that this isn’t a complete list. For your safety, always ask your pharmacist or healthcare provider about possible interactions. Ask your doctor or pharmacist to check your drugs for any important drug interactions. Learn how to recognize the effects of any drug interactions. In case of a drug interaction, learn when you should call your doctor or 911 for emergency help. All medicines come with written instructions. Follow those directions closely. Blood pressure medications, other antihistamines, antidepressants, sleeping pills, bowel disease medications, seizure medications, and cannabis products can have interactions when combined with Benadryl. Alcohol can increase the sedating effect of Benadryl, thus worsening drowsiness, slowing breathing rate, and impairing focus and alertness. Diphenhydramine Interactions. There are 446 drugs known to interact with diphenhydramine, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 14 are major, 430 are moderate, and 2 are minor. The combination of gabapentin and Benadryl (diphenhydramine) is a common concern for individuals managing pain, seizures, or sleep disturbances. While both medications are widely used, their interaction can lead to enhanced side effects, potentially posing significant risks. Phenobarbital. In comparison to cimetidine, phenobarbital presents the opposite problem when it comes to drug interactions. A commonly prescribed anti-seizure medication, phenobarbital makes the body produce more CYP enzymes, which increases the clearance and decreases the effectiveness of many types of medications, including digoxin, glucocorticoids, amitriptyline, clomipramine, theophylline A total of 446 drugs are known to interact with Diphenhydramine: 14 major drug interactions (90 brand and generic names) 430 moderate drug interactions (1668 brand and generic names) 2 minor drug interactions (8 brand and generic names) A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic Applies to: Benadryl (diphenhydramine) and gabapentin. Using diphenhydrAMINE together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. A phase IV clinical study of FDA data: drug interactions are found among 2,435 people who take Gabapentin (gabapentin) and Diphenhydramine hydrochloride (diphenhydramine hydrochloride). The following applies to the ingredients: Diphenhydramine (found in Benadryl) and Gabapentin. MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients. Review detailed drug interaction details between Diphenhydramine and Gabapentin, including severity, interaction details, how to manage the interaction, and more. It’s unclear if there is an interaction between Adderall and clonidine. But, it is important to discuss with your doctor about possible drug interactions. Benadryl (Diphenhydramine) Diphenhydramine is an antihistamine found in over-the-counter products like Benadryl. Benadryl allergy sinus headache is in the drug class upper respiratory combinations. Benadryl allergy sinus headache is used to treat Sinus Symptoms. A total of 270 drugs are known to interact with gabapentin. Gabapentin is in the drug class gamma-aminobutyric acid analogs. When a medication works right, it boosts your health or helps you feel better. But a drug can bring on problems if it doesn't mix well with something else you put into your body, like another Using diphenhydrAMINE together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. It is essential to be aware of potential drug interactions when combining Benadryl and gabapentin. Certain medications, such as opioids or sedatives, may interact with either Benadryl or gabapentin, leading to increased side effects or reduced effectiveness. Lamotrigine Interactions. There are 286 drugs known to interact with lamotrigine, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 10 are major, 264 are moderate, and 12 are minor. There are 363 drugs known to interact with flecainide, along with 5 disease interactions. Of the total drug interactions, 72 are major, 275 are moderate, and 16 are minor. Of the total drug interactions, 72 are major, 275 are moderate, and 16 are minor.
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