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Antiepileptic drugs (AEDs) are associated with rashes and other hypersensitivity reactions. The incidence varies depending on the type of rash, the AED used, and the previous history of rash with quoted incidences ranging from 1.7 to 8.8%. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. A drug rash can develop immediately after starting a new medication, or it can take days or weeks. Drug rashes cause changes in the color or texture of your skin, including things like: Discoloration (like red or brown blotches) Bumps. Peeling. Blistering Some studies suggest gabapentin can cause various types of rashes, including severe rash in children, Exfoliative Dermatitis, cutaneous leukocytoclastic vasculitis, and generalized neutrophilic fixed drug eruption, while other studies indicate it is generally safe for treating postherpetic neuralgia. Rare but serious side effects include rash, itching, yellowing of the skin, swelling of the face and throat, problems speaking, difficulty swallowing and changes in memory, personality or ability While there are different names for different types of severe drug reactions, including Stevens-Johnson syndrome (SJS), drug rash with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP), they are often grouped together as severe cutaneous adverse reactions (SCARs). Apart from gabapentin, there were no other recently introduced medications. Gabapentin is usually a safe and well-tolerated drug with a low incidence of adverse reactions . In opposition to other antiepileptic drugs, skin reactions are rare, and, in adults, the prevalence of rash possibly related to gabapentin varies from 1 to 10% . Classical antiepileptic drugs may cause cross-hypersensitivity reactions. 23,24 However, because of the different chemical structures of gabapentinoids and classic antiepileptic drugs, whether pregabalin and gabapentin have the potential to cause cross-hypersensitivity reactions remains unclear. Based on positive results of the pregabalin Who gets morbilliform drug eruption? About 2% of prescriptions of new drugs cause a drug eruption. About 95% of these are morbilliform drug eruptions.. They mainly affect people prescribed beta-lactam antibiotics (penicillins, cephalosporins), sulfonamides, allopurinol, anti-epileptic drugs and nonsteroidal anti-inflammatory drugs (NSAID). PHN can happen after a person has had shingles, an infection from the same virus as chickenpox that causes a painful rash or blisters. Nerve pain from PHN can last for months, or even longer, after the rash has gone away. An extended-release form of gabapentin is also FDA-approved to treat PHN. Rashes is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Rheumatoid arthritis. It manifests itself as a purple rash that starts as a small spot on the forearm and often spreads from a spot to a larger blotch. If I leave it alone it fades and disappears after a few days. If scratch the itchy rash it seems to be very near the skin surface and bleeds very easily. Discussion: In contrast to other antiepileptic drugs, skin reactions to gabapentin are considered uncommon. In adults, reported prevalence of rash possibly related to gabapentin range from 1% to 10%. A postmarketing surveillance study reported gabapentin treatment failure as a consequence of rash in 0.4% of 3000 patients. Drug rashes, or drug eruptions, are reactions your skin may develop in response to certain drugs. While any drug can cause a rash, certain types are more notorious for causing Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This topic will focus on the clinical presentation, diagnosis, and treatment of exanthematous drug eruptions. Drug hypersensitivity in general, severe cutaneous drug reactions, cutaneous reactions to anticancer agents, and other types of cutaneous adverse drug reactions are discussed separately. Drug hypersensitivity Gabapentin is in a class of medications called anticonvulsants. What are the brand names of gabapentin? Gabapentin is available as both a brand name product and a generic product (chemically the same, usually lower cost than the brand name product). Brand names of gabapentin include Horizant®, Gralise® and Neurontin®. Gabapentin is used to help control partial seizures (convulsions) in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. Do not stop taking gabapentin without first talking to your healthcare provider. Stopping gabapentin suddenly can cause serious problems. Gabapentin can cause serious side effects including: 1. Suicidal Thoughts. Like other antiepileptic drugs, gabapentin may cause suicidal thoughts or actions in a very small number of people, about 1 in 500.
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