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Duloxetine is used to treat depression and anxiety. It is also used for pain caused by nerve damage associated with diabetes (diabetic peripheral neuropathy). Duloxetine is also used to treat fibromyalgia (muscle pain and stiffness) and chronic (long-lasting) pain that is related to muscles and bones. Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive–compulsive disorder, fibromyalgia, neuropathic pain, and central sensitization. [10] [11] It is taken by mouth. [10] Duloxetine is a serotonin–norepinephrine reuptake inhibitor An interaction with duloxetine could cause a serious condition called serotonin syndrome. Duloxetine is not approved for use by anyone younger than 7 years old. To make sure duloxetine is safe for you, tell your doctor if you have: heart problems, high blood pressure; liver or kidney disease; slow digestion; a seizure; bleeding problems; sexual How does duloxetine compare with alternative drugs such as fluoxetine, venlafaxine, and gabapentin? Both duloxetine and venlafaxine ( Effexor XR ) belong to a group of drugs called selective Duloxetine (Cymbalta) can make you sleepy as a side effect. Because of this, avoid driving or doing tasks that require focus until you know how the medication affects you. Don't suddenly stop taking duloxetine (Cymbalta) if this side effect becomes bothersome. Stopping the medication too quickly can lead to sleep issues. Speak with your Approved or recommended drugs in this indication include duloxetine (DLX), pregabalin (PGB), gabapentin (GBP) and amitriptyline (AMT). We conducted an indirect meta-analysis to compare the efficacy and tolerability of DLX with PGB and GBP in DPNP, using placebo as a common comparator. This meta-analysis comprehensively compared the efficacy and safety of duloxetine and gabapentin in the treatment of DPNP using the following outcome measures: VAS score, response rate, incidence of adverse reactions, sleep interference score, and clinical global impression of change impression. My doctor has recently prescribed 30mg of duloxetine daily and I am also taking 800 mg of gabapentin daily. I have been on this combination for a week and would like to hear of others with side effects. Part of the reason for the duloxetine is also a SAD diagnosis. Conclusion: The findings suggest that both duloxetine and gabapentin demonstrate similar effectiveness in managing diabetic neuropathic pain. Duloxetine may help control your symptoms but will not cure your condition. It may take 1 to 4 weeks or longer before you feel the full benefit of duloxetine. Continue to take duloxetine even if you feel well. Do not stop taking duloxetine without talking to your doctor. Your doctor will probably decrease your dose gradually. According to a recent study published in The International Journal of Clinical Practice, there is no significant difference between the use of gabapentin or duloxetine for the treatment of Approved or recommended drugs in this indication include duloxetine (DLX), pregabalin (PGB), gabapentin (GBP) and amitriptyline (AMT). We conducted an indirect meta-analysis to compare the Find patient medical information for Duloxetine (Cymbalta, Drizalma Sprinkle) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Duloxetine related compound a is the latest innovation in pharmaceutical research, offering unmatched quality and purity in every dose. Our product is carefully crafted using state-of-the-art technology to ensure Compare Duloxetine vs Gabapentin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Dry mouth occurred most frequently in patients in patients with generalized anxiety disorder (GAD) or major depressive disorder (MDD) compared to placebo (N=2995). Nausea occurred most frequently in patients given 60 mg orally 2 times a day (N=225); the side effect occurred in 22% of patients given 60 mg orally once a day, and in 14% of Gralise (gabapentin) and Cymbalta (duloxetine) are used to treat different types of neuralgia (nerve pain). Gabapentin is used postherpetic neuralgia from herpes zoster (nerve damage from shingles) and to treat seizure disorders. Compare Cymbalta vs Gabapentin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Alcohol may worsen the side effects of duloxetine such as drowsiness, dizziness, and liver toxicity. Note that this list is not all-inclusive and includes only common medications that may interact with duloxetine. You should refer to the prescribing information for duloxetine for a complete list of interactions. Related/similar drugs Although both gabapentin and duloxetine can treat chronic pain, particularly neuropathic pain, they come from distinct classes, possess different mechanisms, and treat a variety of conditions beyond just nerve issues. Understanding these differences is crucial for selecting the appropriate therapy.
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