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Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Gabapentin is eliminated from the systemic circulation by renal excretion as unchanged drug. Gabapentin is not appreciably metabolized in humans. Gabapentin elimination half-life is 5 to 7 hours and is unaltered by dose or following multiple dosing. Gabapentin elimination rate constant, plasma clearance, and renal clearance are directly Each gabapentin capsule contains 100 mg, 300 mg, or 400 mg of gabapentin and the following inactive ingredients: anhydrous lactose, cornstarch, and talc. The 100 mg capsule shell contains gelatin, sodium lauryl sulfate, and titanium dioxide. The 300 mg capsule shell contains gelatin, sodium lauryl sulfate, titanium dioxide, and yellow iron oxide. What Is Gabapentin and How Does It Work? Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults, treating the pain of post herpetic neuralgia. Gabapentin belongs to a class of drugs known as anti- seizure drugs. Gabapentin caused a marked decrease in neuronal synapse formation in brains of intact mice and abnormal neuronal synapse formation in a mouse model of synaptic repair. Gabapentin has been shown in vitro to interfere with activity of the α2δ subunit of voltage-activated calcium channels, a receptor involved in neuronal synaptogenesis. The Gabapentin is used to help control partial seizures (convulsions) in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. GABAPENTIN CAPSULES, USP, 100 mg, 300 mg and 400 mg GABAPENTIN TABLETS, USP, 100 mg, 300 mg, 400 mg, 600 mg and 800 mg Manufactured by Manufactured for Apotex Inc. Apotex Corp. Toronto, Ontario Weston, Florida Canada M9L 1T9 33326 Revised: June 2015 Rev. 2 Gabapentin is commonly used to treat and prevent seizures in people with epilepsy or to treat nerve pain (postherpetic neuralgia) that can occur after a viral infection called shingles. PACKAGE LEAFLET: INFORMATION FOR THE PATIENT Gabapentin 100 mg and 300 mg Capsules Gabapentin Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Keep this leaflet. You may need to read it again. • If you have any further questions, ask your doctor or pharmacist. Generic name: gabapentin [ GA-ba-PEN-tin ] Drug class: Gamma-aminobutyric acid analogs. Medically reviewed by Philip Thornton, DipPharm. Last updated on Feb 21, 2025. Uses; Warnings; Before taking; Dosage; Side effects; Interactions; FAQ; What is Neurontin? Neurontin is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals During the controlled epilepsy trials in patients older than 12 years of age receiving doses of gabapentin up to 1,800 mg daily, somnolence, dizziness, and ataxia were reported at a greater rate in patients receiving gabapentin compared to placebo: i.e., 19% in drug versus 9% in placebo for somnolence, 17% in drug versus 7% in placebo for Gabapentin (Gralise, Gralise 30-Day Starter Pack, and Neuraptine) is an anti-seizure (anticonvulsant) medication used to treat: Seizure disorders; Postherpetic neuralgia, the pain that comes after an episode of shingles; Off-label uses (uses that are not approved by the Food and Drug Administration, or FDA) for gabapentin include: Alcohol Concurrent drug therapy issues: Drug-drug interactions: Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy. Consult drug interactions database for more detailed information. Dosage form specific issues: To report SUSPECTED ADVERSE REACTIONS, contact Pfizer, Inc. at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. Gabapentin (Neurontin, Gralise, Horizant) is a medicine used to treat partial seizures, nerve pain from shingles and restless leg syndrome. It works on the chemical messengers in your brain and nerves. Gabapentin is from a group of medicines called anticonvulsants. For healthcare professionals. Applies to gabapentin: compounding powder, oral capsule, oral solution, oral tablet, oral tablet extended release. General adverse events. The most common adverse reactions associated with the use of this drug were dizziness, somnolence, and peripheral edema. Gabapentin is in a class of medications called anticonvulsants. Gabapentin treats seizures by decreasing abnormal excitement in the brain. Gabapentin relieves the pain of PHN by changing the way the body senses pain. It is not known exactly how gabapentin works to treat restless legs syndrome. Gabapentin (Neurontin) is a prescription drug. It comes as an oral capsule, an immediate- or extended-release oral tablet, and an oral solution. The drug information contained herein is Gabapentin is a medication that treats nerve pain by calming overactive nerves in your body. It may also prevent and control seizures in people with epilepsy. You can take this medication by mouth with a glass of water. Gabapentin tablets are indicated for: Patients 3 to 11 years of age: starting dose range is 10 to 15 mg/kg/day, given in three divided doses; recommended dose in patients 3 to 4 years of age is 40 mg/kg/day, given in three divided doses; the recommended dose in patients 5 to 11 years of age is 25 to 35 mg/kg/day, given in three divided doses.
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