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Vitamin B12. A total of 15 drugs are known to interact with Vitamin B12. Vitamin b12 is in the drug class vitamins. Vitamin b12 is used to treat the following conditions: B12 Nutritional Deficiency; Pernicious Anemia; Schilling Test; Vitamin B12 Deficiency; Drug and food interactions Vitamin D is an important nutrient that helps keep your body running. Vitamin D deficiency can cause weak bones and lead to a number of other health problems. Some common medications can lower vitamin D levels — like seizure medications, antibiotics, and blood pressure medications. Individuals on long-term multiple anticonvulsant therapy may develop below-normal blood levels of calcium, which may be related to drug-induced vitamin D deficiency. Two infants born to women taking high doses of phenytoin and phenobarbital while pregnant developed jitteriness and tetany (a syndrome characterized by muscle twitches) cramps, and spasm during the first two weeks of life. Drugs like prednisone and gabapentin (Neurontin) alter vitamin D activity. Milk and a supplement are probably not nearly enough to counteract the complications of these medicines. Anyone have any thoughts on vitamin D deficiency bought on by anti epileptic drugs. I am on Gabapentin and just learned that it can deplete the body of magnesium. I was just reading this article which says if on these drugs you should take at least 7,000 vit D per day. The induction of CYP450 isoenzymes may cause vitamin D deficiency, hypocalcemia, increased fracture risks, and altered bone turnover, leading to impaired bone mineral density (BMD). Newer AEDs, such as levetiracetam (LEV), oxcarbazepine (OXC), lamotrigine (LTG), topiramate (TPM), gabapentin (GP), and vigabatrin (VB) have broader spectra, and Drugs that activate the pregnane X receptor can disrupt vitamin D metabolism and vitamin D function. Beside this, the medication oriented supplementation of vitamin D can ameliorate the pharmacologic action of some drugs, such as bisphosphonates, cytostatics and statins. Treatment with cholecalciferol may require you to adjust your dietary intake of foods which contain natural or added calcium, phosphate (organic and inorganic), and vitamin D. Ingesting too much vitamin D or having elevated calcium and/or phosphorus levels in the blood and urine can lead to toxic effects, such as having an irregular heart rhythm, seizures, kidney stones, and eventual Gabapentin causes drug-nutrient depletions, meaning it can reduce the body’s levels of certain nutrients and that can lead to side effects. It’s not a bad thing, it just is. Medications have the ability to deplete or reduce nutrients from the body or interfere with how it works. Prophylactic Vitamin D doses up to 2000 IU/day can be given in all patients at the beginning of treatment. Calcium intake in doses of 600–1000 mg/day should also be ensured. In case of osteopenia or osteoporosis, treatment with 2000–4000 IU/day Vitamin D is appropriate. Vitamin D doses may be increased in cases of osteomalacia. Vitamin D is essential for the proper development and maintenance of bone. Serum 25 (OH)D concentration is the most commonly used index of vitamin D status, and reduced levels are seen in both adults and children taking AEDs (4, 11, 20, 23, 26, 27, 28, 29, 30, 31). While there are no known interactions between vitamin D and gabapentin, it’s always best to consult with your healthcare provider before starting any new supplement or medication regimen. They can provide personalized advice based on your specific needs and medical history. Don’t miss out on the potential benefits of vitamin D and gabapentin. Although there is controversy as to the definition of vitamin D deficiency and appropriate treatment (Rosen et al., 2012b), the Endocrine Society defines vitamin D deficiency as a 25-hydroxyvitamin D level <20ng/ml (Holick et al., 2011). 3 The Endocrine Society recommends that vitamin D deficiency be treated with 50,000 IU of vitamin D once a View drug interactions between gabapentin and Vitamin D3. These medicines may also interact with certain foods or diseases. Gabapentin is in the drug class gamma-aminobutyric acid analogs. A total of 17 drugs are known to interact with Vitamins. Vitamins is in the drug class vitamin and mineral combinations. Vitamins is used to treat Dietary Supplementation. While Vitamin D and Gabapentin serve different purposes, there is evidence to suggest that combining them may have synergistic effects. Some potential benefits of this combination include: Enhanced pain relief: Gabapentin can help alleviate nerve pain, and Vitamin D may contribute to reducing inflammation and improving overall pain management.
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