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Summary: High blood sugar is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Depression. The short answer is: yes, it is possible, though not very common, for gabapentin to raise your blood sugar. Studies have shown that approximately 1.2% of patients treated with gabapentin may experience hyperglycemia (high blood sugar) compared to 0.4% with a placebo. When considering the use of Gabapentin for diabetics, several potential benefits arise: Pain Relief: Many diabetics suffer from neuropathic pain due to nerve damage caused by high blood sugar levels. Gabapentin can significantly reduce this pain. Improved Sleep: Chronic pain often disrupts sleep patterns. By alleviating discomfort, Gabapentin Steroids — either as pills or injection — can raise blood sugar levels while you’re taking them (this is much less likely with inhaled steroids). This can be a problem in people who already have diabetes and in people who don’t have diabetes. Increased blood sugar is more likely if you take higher doses of steroids over the long term. The SmPC of gabapentin mentions blood glucose fluctuations in diabetic patients as a potential adverse drug reaction with unknown frequency [1]. The current observation describes the association between gabapentin and severe hypoglycaemia in diabetic and non-diabetic patients. Reports While there is evidence suggesting that gabapentin can potentially raise blood sugar levels in some individuals, particularly those with pre-existing diabetes, there are also multiple reports of gabapentin causing hypoglycemia. CONCLUSIONS: Hypoglycemia is a rarely acknowledged adverse effect of gabapentin overdose and requires urgent intervention as it could be initially resistant to simple glucose replacement and may lead to serious consequences. In this case, blood glucose levels responded only to high concentration dextrose infusion (D10) with concomitant tube feeds. Gabapentin has not been reported to raise blood sugar, however it would be best to consult a pharmacist/doc who would have prescribed the med. Take care, be well & safe! Votes: +0 Gabapentin is used to control seizures, to treat nerve pain that can happen after having had shingles, and to treat a condition called restless legs syndrome. In addition to these FDA-approved uses, doctors sometimes prescribe gabapentin off-label. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Rare but serious gabapentin side effects include mood changes in children. Hyperglycemia is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Depression. Gabapentin appears to have effects on several voltage-gated calcium channels. Hypoglycemia may be due to gabapentin binding to the alpha<sub>2</sub>delta subunit of the calcium channels in the pancreas. Future research should investigate gabapentin and the potential for hypoglycemia. Gabapentin appears to have effects on several voltage-gated calcium channels. Hypoglycemia may be due to gabapentin binding to the alpha 2 delta subunit of the calcium channels in the pancreas. Future research should investigate gabapentin and the potential for hypoglycemia. 1 Answer - Posted in: gabapentin, dosage, blood disorders - Answer: Hi.. yes..High Blood Sugar rare side effects of Neurontin.. please consult Gabapentin, a medication commonly used for neuropathic pain, has been associated with varying effects on blood sugar levels. This article synthesizes findings from multiple case reports to provide a comprehensive understanding of how gabapentin may influence blood glucose, highlighting both hypoglycemia and hyperglycemia. Despite adequate pain control achievement following gabapentin initiation, blood glucose values continued to rise. From a search of the medical literature, 2 articles speak to the effect of gabapentin on blood glucose levels. Her blood glucose level was 33 mg/dL. Gabapentin was started 1 week prior to the hypoglycemia episode. Her past medical history, concomitant medications, and other laboratory findings were not likely causes of her severe hypoglycemia. Began some medical journal research and found an obscure paper indicating that, in rare instances, gabapentin may cause lowering of blood sugar. Since then my oral blood sugar medication requirements have dropped significantly. askyourpharm.com Hypothetically, gabapentin-induced GABA A receptor activation could stimulate insulin release resulting in hypoglycaemia. Alternatively, direct binding to the alpha 2 -delta 2 receptor of the voltage-gated calcium channels could also provide a pharmacological explanation.
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