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Interestingly, studies show that gabapentin and mirtazapine have similar effects on food intake in cats, indicating a synergy in their action to stimulate appetite. If your cat’s appetite remains poor even with gabapentin, your vet may recommend combination therapy to encourage them to eat more. This double-blind, placebo-controlled study investigated the effect of gabapentin on appetite in healthy hospitalized cats following ovariectomy. Sixty cats received gabapentin (5 mg/kg PO), mirtazapine (1.88 mg/cat PO), or placebo. Food was offered 2-, 4-, 6-, and 8-hours postoperation, and intake was measured. Conclusions and relevance: Cats receiving gabapentin ate more than cats in the placebo group. Thirty percent of cats in the gabapentin group covered their resting energy requirements, while none of the cats in the placebo group did. Gabapentin and mirtazapine produced similar effects on food intake. Initially, in dogs and cats, gabapentin was used extra-label as an antiepileptic drug, but now it is more commonly used for chronic and neuropathic pain management in companion animals, despite the lack of evidence of efficacy and the lack of correspondence of neuropathic pain conditions in human and animals. A study involving 47 hyperthyroid cats revealed that cats receiving a gabapentin dose of 20 mg/kg were notably more relaxed during transport and compliant during veterinary procedures. This outcome underscores gabapentin’s effectiveness as an anxiolytic, showcasing its ability to reduce stress and improve compliance in clinical settings If your cat is taking gabapentin in capsule or tablet form, mix the prepared powder with a small amount of your cat’s favorite food or a bit of water so they can swallow it easily. If using the liquid form, use the syringe to carefully administer the medication directly into your cat’s mouth, slowly squirting it near the back of the tongue. 7. Does gabapentin cause appetite changes in cats? Yes, some cats may experience an increase in appetite after taking gabapentin. 8. Can gabapentin cause any changes to my cat’s behavior? While the intended effect is calming, some cats might become more clingy or disoriented while the medication is in effect. 9. Gabapentin was compared with mirtazapine in this study because of the latter’s demonstrated appetite-stimulating effect in cats: the same dose of 1.88 mg/cat PO used in the present work showed positive effects on appetite, weight gain and reduction of vomiting in cats with CKD. 31 In the cited study, appetite was documented by the owners via In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. Yes, gabapentin can stimulate appetite in cats, although it’s not its primary use. While more commonly prescribed for pain management, anxiety, and seizure control, research and anecdotal evidence indicate that gabapentin can have an appetite-stimulating effect in felines. Increased Appetite: Interestingly, gabapentin has been shown to increase appetite in some cats. These side effects are generally mild and temporary. If you notice these in your cat, or any other concerning changes after administering gabapentin, please contact your veterinarian . Studies have shown that cats on gabapentin tend to eat more than those on a placebo. A notable study indicated that 30% of cats receiving gabapentin met their resting energy requirements, while none of the cats in the placebo group did.
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