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Gabapentin is usually used to manage chronic pain, especially nerve-related pain. It is also used (primarily in cats) to relieve anxiety associated with veterinary procedures, travel, and other fear-generating situations. Gabapentin can also be used as an additional medication in seizure management. The cat was treated with a short course of an unknown analgesic for suspected feline lower urinary tract disease (FLUTD), after which the cat displayed no lower urinary signs. Approximately 3 weeks prior to presentation at PennVet, the cat presented to the pDVM for evaluation of weight loss and hyporexia. Ten days after she began taking gabapentin to relieve her pain, she experienced daily urinary incontinence. In another instance, a 63-year-old female patient was diagnosed with complex regional pain syndrome, and seven days after the initiation of gabapentin therapy, urinary incontinence developed. Less than 5% of FLUTD cats have Bacterial Urinary Tract Infections. Cat urine normally dicourages bacterial growth. Only cats that are producing abnormal urine are prone to developing lower urinary tract infections. Cats may develop a urinary tract infection if they have very dilute urine from chronic kidney disease, glucose in the urine from Gabapentin can be a valuable tool in managing urinary issues in cats, particularly those with FLUTD. While it doesn’t address the underlying cause of the problem, it effectively reduces the pain associated with it, leading to improved comfort and quality of life. urethroliths guides the approach to urinary catheter placement and bladder decompression (FIGURE 1). MANAGEMENT STRATEGIES Managing Feline Urethral Obstruction Kelly St. Denis , MSc, DVM, DABVP (Feline Practice) Charing Cross Cat Clinic, Brantford, Ont. Krishantha Madumal/shutterstock.com BOX 1 Factors Predisposing to Feline Urethral Obstruction Tony Buffington, DVM, MS, PhD, DACVN, and Jodi Westropp, DVM, PhD, the gurus of all things lower urinary tract, have coined the term “Pandora's syndrome” to describe sensitization and upregulation of the feline stress response that's often most dramatically manifested in the urinary bladder. When a sensitized cat is put in a provocative Tigger continued the buprenorphine, clavamox, prazosin and gabapentin at home as prescribed. Cats who have a history of obstructions are at a higher risk of becoming obstructed in the future. Studies have found that cats on a dry food diet, in a multi-cat home, or in a stressful environment have an increased risk of developing a urinary Gabapentin should be used cautiously in cats with liver or kidney disease, as we may see it take longer for the effects to wear off. Its use should typically be avoided in pregnant queens. For decades, FIC was felt to be dietary in origin. In fact, when feline commercial foods were reformulated in the 1980s to create a more acid urinary pH, the incidence of feline cystitis dropped spectacularly. Urinary crystals (usually struvite) are important in the male cat syndrome of urinary obstruction, which is a complication of FIC 3. Hall J, Hall K, Powell L, et al. Outcome of male cats managed for urethral obstruction with decompressive cystocentesis and urinary catheterization: 47 cats. J Vet Emerg Crit Care 2015;25(2):256-262. 4. Cooper ES, Owens TJ, Chew DJ, et al. A protocol for managing urethral obstruction in male cats without urethral catheterization. Feline idiopathic cystitis, also known as feline interstitial cystitis or FIC for short, is a type of feline lower urinary tract disease that causes inflammation of the bladder in cats. “Idiopathic” means that the cause of the disease process is unknown; “interstitial” refers to the location of the inflammation in the interstitium Gabapentin should be used cautiously in cats with significant liver or kidney disease, since it may take longer for the effects to wear off. Avoid giving gabapentin to pregnant or nursing cats. Gabapentin can cross the placenta and enter the mother’s milk. Gabapentin as a treatment for idiopathic cystitis: Idiopathic cystitis is a common urinary condition in cats that can cause pain and discomfort. Gabapentin has been used successfully to manage the symptoms of idiopathic cystitis in felines, helping to alleviate pain and improve the cat 's quality of life. One of the main benefits of using gabapentin for cats with urinary crystals is its ability to alleviate pain and discomfort. Cats with urinary crystals often experience pain while urinating, and gabapentin can help reduce this pain by blocking certain nerve signals in the brain. What is gabapentin used for in cats? Gabapentin is an anticonvulsant and analgesic drug used to treat chronic pain in cats, dogs, and horses. The drug has been shown to be especially efficient in treating neuropathic pain in cats, usually in conjunction with other analgesic agents like nonsteroidal anti-inflammatory drugs (NSAIDs). Gabapentin
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