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Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Perhaps most concerning is the risk of suicidal thoughts or behaviors. While this is rare, it’s a serious potential side effect that shouldn’t be ignored. It’s like a dark cloud that can appear on even the sunniest days, and it’s crucial to be aware of this risk. The Perfect Storm: Factors Influencing Gabapentin’s Mental Side Effects Common side effects of gabapentin include: Feeling tired. Dizziness. Headache. Nausea and vomiting. Fever. Difficulty speaking. Recurring infections. Memory loss. Weight gain. Movement problems: coordination problems, being unsteady, tremors, jerky movements. Eye problems: unusual eye movements, double vision. Talk to your healthcare provider As with any medication, there may be some side effects. Some of these are more likely to happen when you first start taking the medication. Common side effects: Dizziness. Double Vision. Side Effects of Gabapentin. Like any medication, gabapentin has a range of side effects. These can range from common physical symptoms to less frequent, but more serious, psychiatric effects. It's important to understand these potential side effects when discussing the question, 'can gabapentin cause depression?'. Psychiatric Effects Common side effects of gabapentin include: flulike symptoms such as fever or body aches. Rare but serious side effects of gabapentin include: changes in memory, ability to concentrate, or personality. Gabapentin may cause breathing problems in people who use opioid pain medicines and those with chronic obstructive pulmonary disease (COPD). Gabapentin can affect mood and may cause depressive symptoms, though this is considered a rare side effect. While it is primarily used to treat seizures and nerve pain, some individuals have reported experiencing feelings of sadness or worsening depression during treatment. Depression is a serious, yet uncommon, side effect of using gabapentin. It can either cause depression or make existing cases of depression worse. Individuals have a higher risk of developing depression as a side effect if they already have a history of a psychological disorder. Gabapentin, one of the antiepileptics, shows its effects via voltage-gated calcium channels. Sedation and mood elevation are among its side effects. Gabapentin can help control seizures as well as nerve pain from shingles. It may sometimes cause side effects, especially if you misuse it. Learn more. Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Watch for breathing issues The most common side effects of gabapentin in therapeutic doses are drowsiness, somnolence, dizziness, movement disorders, diarrhea, and weight gain. In addition, cases have been reported of gabapentin-related suicidal acts and aggressive behavior [ Table 1 ]. Gabapentin is primarily an anticonvulsant medication, yet its association with psychiatric side effects, including depression, has garnered attention. While classified as serious but uncommon, reports indicate that depression can be exacerbated in individuals with a history of psychological issues. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. The prevalence of depression as a side effect of gabapentin use is difficult to pinpoint precisely, as it can vary depending on the patient population and study methodology. However, it’s estimated that between 1% and 10% of patients taking gabapentin may experience depression as a side effect. It’s as if gabapentin decided to invite the gloomiest rain cloud to your mental picnic. These feelings can range from a persistent low mood to more severe depressive symptoms. In some cases, patients may experience thoughts of self-harm or suicide. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects. 4. Bottom Line. Gabapentin is an anticonvulsant with pain
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