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Gabapentin, one of the antiepileptics, shows its effects via voltage-gated calcium channels. Sedation and mood elevation are among its side effects. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. As with any medication, there may be some side effects. Some of these are more likely to happen when you first start taking the medication. Typically, your doctor will prescribe 300 mg once a Safety reports of gabapentin and pregabalin should be obtained from concerned manufacturers and reviewed for respiratory depression effects. There should be strict prescription monitoring and drug use evaluation studies. Concurrent use of gabapentin and pregabalin with other respiratory depressants such as opioids should be strictly monitored. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Side Effects of Gabapentin. Like any medication, gabapentin has a range of side effects. These can range from common physical symptoms to less frequent, but more serious, psychiatric effects. It's important to understand these potential side effects when discussing the question, 'can gabapentin cause depression?'. Psychiatric Effects Gabapentin can affect mood and may cause depressive symptoms, though this is considered a rare side effect. While it is primarily used to treat seizures and nerve pain, some individuals have reported experiencing feelings of sadness or worsening depression during treatment. Gabapentin can help control seizures as well as nerve pain from shingles. It may sometimes cause side effects, especially if you misuse it. Learn more. Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Watch for breathing issues Some side effects of Gabapentin are common, but are typically not serious and can be treated at home. These symptoms include abnormal eye movements, dizziness, fever, unsteadiness, diarrhea, constipation, drowsiness, dry mouth, difficulty speaking, nausea, and vomiting. When Your Brain Goes Rogue: Neurological Side Effects. Now, let’s venture into the realm of neurological side effects – because apparently, messing with our emotions wasn’t enough for gabapentin. These effects can have a significant impact on our mental well-being, even if they’re not directly classified as “mental” side effects. The prevalence of depression as a side effect of gabapentin use is difficult to pinpoint precisely, as it can vary depending on the patient population and study methodology. However, it’s estimated that between 1% and 10% of patients taking gabapentin may experience depression as a side effect. The most common side effects of gabapentin in therapeutic doses are drowsiness, somnolence, dizziness, movement disorders, diarrhea, and weight gain. In addition, cases have been reported of gabapentin-related suicidal acts and aggressive behavior [ Table 1 ]. Furthermore, other measurements of mood, depression, anger-hostility, fatigue, and physical functioning were more effectively managed with gabapentin compared to a placebo. During the same time, Backonja et al reviewed the effect of gabapentin in 165 diabetic neuropathy patients. Gabapentin is primarily an anticonvulsant medication, yet its association with psychiatric side effects, including depression, has garnered attention. While classified as serious but uncommon, reports indicate that depression can be exacerbated in individuals with a history of psychological issues. What are the more common side effects of gabapentin? Common side effects of gabapentin include: Feeling tired. Dizziness. Headache. Nausea and vomiting. Fever. Difficulty speaking. Recurring infections. Memory loss. Weight gain. Movement problems: coordination problems, being unsteady, tremors, jerky movements. It’s as if gabapentin decided to invite the gloomiest rain cloud to your mental picnic. These feelings can range from a persistent low mood to more severe depressive symptoms. In some cases, patients may experience thoughts of self-harm or suicide. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects. 4. Bottom Line. Gabapentin is an anticonvulsant with pain Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
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