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Concurrent Disease: Based on human information, use this drug cautiously in cats with liver disease, kidney disease (dose reduction may be required since drug is renally eliminated), congestive heart failure, or seizure disorders. Interactions: Trimethoprim/sulfa combination drugs may decrease excretion of amantadine, yielding higher blood levels. Approximately 90 minutes prior to placing the cat in the carrier to visit the veterinarian, companion cat parents administer 100 mg of gabapentin (20 mg/kg) orally to their cats to help facilitate transfer, reduce stress, and increase examination compliance. Objectives: The purpose of this study was to assess serum concentrations of gabapentin in cats with chronic kidney disease (CKD) vs clinically healthy cats. Methods: Five healthy cats were enrolled in a pharmacokinetic study. A single 20 mg/kg dose of gabapentin was administered orally and blood was obtained at 0, 0.25, 0.5, 1, 1.5, 2, 3, 4, 8 It is recommended that you gradually increase the medication dose over time to alleviate these effects. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. Are there any risk factors for this medication? Gabapentin should NOT BE USED in pets that are allergic to it. Gabapentin does have some anti-seizure effects, but it is not considered a first-choice option for seizure disorders in cats. Other medications are typically prescribed first to control seizures. Gabapentin may be used in cats as add-on therapy. Gabapentin and Kidney Disease. It’s essential to exercise caution when using gabapentin in cats with chronic kidney disease (CKD). Higher doses can lead to excessive sedation and hypotension in these patients. A dose decrease of at least 50% is often used in these cases. It’s imperative to consult with your veterinarian if your cat has CKD. Long-term use of gabapentin for musculoskeletal disease and trauma in three cats (2013) Lorenz ND, Comerford EJ & Iff I Journal of Feline Medicine and Surgery 15(6) pp507-12 states that "All cats received gabapentin for several months at an average dose of 6.5 mg/kg q12h." Managing pain in dogs with kidney disease can be challenging, as many medications can worsen kidney function. Finding safe and effective pain relief requires a thoughtful, well-balanced approach to avoid aggravating your dog’s kidney condition while still alleviating discomfort. Key Takeaways: Quick Answers for Dogs with Kidney Disease What’s the safest pain medication? 🩺 Gabapentin and Gabapentin should be used cautiously in cats with liver or kidney disease, as we may see it take longer for the effects to wear off. Its use should typically be avoided in pregnant queens. Gabapentin Dosage for Cats Is gabapentin bad for cats with kidney disease? Cats with chronic kidney disease (CKD) exhibit higher serum concentrations of gabapentin, indicating a need for dose adjustment. It’s essential to administer lower doses to avoid potential toxicity and monitor their response closely. This is an open forum for owners of cats with kidney disease as well as others who have something to contribute. Feel free to share pictures and stories, as well as a friendly helping hand to those who need it. But remember, we are not a replacement for a vet. We are for support only. An early study concluded that a dose of 20mg/kg was effective for this purpose in healthy cats, but this dose may be inappropriate for elderly cats, specifically those with chronic kidney disease (CKD). Human studies have recommended Gabapentin doses be reduced in CKD patients, but no studies have been done in cats. management, even in older cats with chronic renal failure.15 • Twenty-two cats with chronic renal failure (median age, 15.5 years) received meloxicam for a median treatment duration of 467 days, with titration to the lowest effective dose. • The results suggested that a long-term daily dose of 0.02 mg/kg can be safely administered Gabapentin is used in cats to treat chronic pain, especially of neuropathic origin and anxiety. For pain, this drug seems to be most effective when combined with other types of analgesics (for Gabapentin is cleared by the kidneys, and in a cat with kidney disease, drug levels are increased, which explains the excess sedation. Good news is that she cant overdose on gabapentin. Tell your vet to lower the dose. Source: pharmacist. 100mg is what was prescribed to me also but I give my cat 50mg 2hours before the car ride. Customized Dosing: Veterinarians are now tailoring gabapentin dosages to individual cats with kidney disease, taking into account factors such as age, weight, and overall health. This personalized approach has shown promising results in managing pain and discomfort in cats with kidney disease. 3. 5. Can gabapentin cause kidney problems in cats? High doses of gabapentin, particularly in cats with chronic kidney disease, can be problematic. It’s essential to adjust the dosage in these cases. 6. Will gabapentin make my cat hungry? Yes, studies show that gabapentin may increase food intake in some cats. 7. The 20 mg/kg stress-reduction dose of gabapentin may be beneficial to facilitate preventive veterinary care in younger, healthy cats, but this dose may be inappropriate for elderly cats, specifically those with chronic kidney disease (CKD). What is the recommended gabapentin dosage for cats with kidney disease? While the standard dosage for healthy cats is 20mg/kg, cats with chronic kidney disease (CKD) should be given a reduced dose of 10mg/kg. The question of whether gabapentin is safe for cats with chronic kidney disease (CKD) is complex and requires careful consideration. The short answer is: it can be safe when used judiciously, but it’s not without risks and requires dosage adjustments due to the kidneys’ role in its elimination.
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