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Gabapentin can cause a serious condition called multiorgan hypersensitivity or Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. If experiencing symptoms such as rash, fever, swollen lymph nodes, or liver problems, medical attention should be sought immediately. It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have sex and loss of ability to have an orgasm) has been reported among women who take gabapentin. Does taking gabapentin increase the chance of miscarriage? People with a history of drug or alcohol abuse⁚ Gabapentin may be habit-forming in people with a history of drug or alcohol abuse. Pregnant women⁚ Gabapentin should be used during pregnancy only if the potential benefit to the mother outweighs the potential risk to the fetus. Breastfeeding women⁚ Gabapentin passes into breast milk Gabapentin is an anti-epileptic drug, also called an anticonvulsant. Drug class: Gamma-aminobutyric Gabapentin pregnancy and breastfeeding warnings (more detail) It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have sex and loss of ability to have an orgasm) has been reported among women who take gabapentin. This article summarizes the current literature regarding gabapentin use during pregnancy and related prenatal and neonatal exposure outcomes with special consideration for interactions between gabapentin and opioid use. Abstract Background. Despite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes. There's no evidence to suggest that taking gabapentin reduces fertility in either men or women. However, discuss your pregnancy plans with a doctor. They may wish to review your medicine and prescribe a higher dose of folic acid for you to take (5mg a day) before you become pregnant. Animal studies have shown that gabapentin intake during pregnancy increases the risk of embryo fetal toxicity, specifically on mice. For rats, adverse effects on offspring development were common among those who had gabapentin during pregnancy. Pregnancy-related problems, such as preterm delivery (birth before week 37) or low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth) have been reported in some studies looking at the use of gabapentin during pregnancy. Background: Despite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes. Pregnancy category: AU: B1 [2] Dependence liability: Physical: High [3] there was an increase in gabapentin-only and multi-drug use from 2012 to 2015. The Advice and warnings for the use of Gabapentin during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out 7.1 Other Antiepileptic Drugs 7.2 Opioids . 7.3 Maalox ® (aluminum hydroxide, magn esium hydroxide) 7.4 Drug/Laboratory Test Interactions . 8 USE IN SPECIFIC POPULATIONS . 8.1 Pregnancy . 8.2 Lactation 8.4 Pediatric Use . 8.5 Geriatric Use 8.6 Renal Impairment . 9 DRUG ABUSE AND DEPENDENCE . 9.1 Controlled Substance . 9.2 Abuse 9.3 Dependence days), the drug should be stopped several months before conception to avoid exposure in early gestation. Excreted into milk. Unknown effects on nursing infants and breast feeding is not recommended because of high iodine content in the drug. The U.S. Food and Drug Administration classifies gabapentin (Neurontin) as a Pregnancy Category C medication, which means that animal studies conducted on this medication has caused harm on the fetus. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antiepileptic drugs (AEDs), such as GABARONE, during pregnancy. Encourage women who are taking GABARONE during pregnancy to enroll in the North American Antiepileptic Drug (NAAED) Pregnancy Registry by calling the toll free-number 1-888-233-2334 or Example drugs: gabapentin, amlodipine, trazodone. Category D. There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Example drugs: losartan. Category X Following concerns about abuse, gabapentin has been reclassified as a Class C controlled substance and is now a Schedule 3 drug, but is exempt from safe custody requirements. Healthcare professionals should evaluate patients carefully for a history of drug abuse before prescribing gabapentin, and observe patients for signs of abuse and dependence. Following concerns about abuse, gabapentin has been reclassified as a Class C controlled substance and is now a Schedule 3 drug, but is exempt from safe custody requirements. Healthcare professionals should evaluate patients carefully for a history of drug abuse before prescribing gabapentin, and observe patients for signs of abuse and dependence.
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