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Are there any serious interactions with gabapentin and other medications? Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Some examples include narcotic opioids, anti-anxiety medicines, antidepressants, and antihistamines. Concomitant use of alcohol with gabapentin may cause excessive sedation, somnolence, and respiratory depression. Alcohol causes a more rapid release of gabapentin enacarbil from the extended-release tablets that may increase the risk for adverse events. Drug-food and drug-drink interactions: Food and drinks can change how medicines work or worsen side effects when they are combined. Examples include beverages like grapefruit juice and statins causing muscle pain, or alcohol and opioids leading to dangerously slowed breathing. Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Immediate-release forms of gabapentin (Neurontin, generic gabapentin) can be taken with or without food. The longer-acting forms of gabapentin (Horizant, Gralise) should be taken with food or a meal to help improve the absorption of the medicine. What to avoid Avoid driving or hazardous activity until you know how gabapentin will affect you. Your reactions could be impaired. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Comprehensive alcohol & food interactions for Gralise (gabapentin). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Generic Name Gabapentin DrugBank Accession Number DB00996 Background. Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. 8 There are no specific foods to avoid while taking gabapentin in terms of drug/food interactions. However, if you’re taking gabapentin for seizures or nerve pain, a general, anti-inflammatory diet is recommended to support nerve and overall health. There is 1 alcohol/food/lifestyle interaction with gabapentin. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. There are 4 disease interactions with gabapentin. Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Find patient medical information for Gabapentin (Gralise, Neurontin) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Understanding drug interactions is crucial when managing medications, especially when dealing with drugs like gabapentin. Gabapentin, often prescribed for nerve pain, seizures, and other conditions, can interact with a range of other medications, sometimes leading to adverse effects. It’s essential to be aware of these potential interactions Comprehensive alcohol & food interactions for Neurontin (gabapentin). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Amlodipine Interactions. There are 535 drugs known to interact with amlodipine, along with 4 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 23 are major, 474 are moderate, and 38 are minor. Drug Interactions between gabapentin and ibuprofen. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. Drug-food/drink interaction. This is when something you eat or drink affects a drug. For instance, it can be dangerous to drink alcohol while you're on certain medications. Some vitamins 270 medications are known to interact with gabapentin. Includes: drug, food, pregnancy, breastfeeding and therapeutic duplication warnings.
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