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Developed by The Pain Team, Tayside Integrated Pain Service, and has been reviewed by other staff and patients Reviewed 02/2008 Review 02/2010 LN0871 Gabapentin Patient Information Tayside Integrated Pain Service Ninewells Hospital Tel. 01382 425612 Perth Royal Infirmary Tel. 01738 473492 Stracathro Hospital Tel. 01356 647291 Gabapentin is a drug used to treat nerve pain. This type of pain is often not relieved by normal painkillers. It can be used in combination with other painkillers to improve your pain relief. How does gabapentin work? Gabapentin works by changing the way in which nerves send messages to your brain. Some lower back pain is made up of a combination of musculoskeletal and neuropathic symptoms so gabapentin or pregabalin can be used as initial treatment options in these cases. To achieve substantial benefit in post-herpetic neuralgia, the NNT is 6.7. Gabapentin is used to help reduce pain. It is especially good for nerve pain, such as burning, shooting, stabbing, pins and needles, crawling, electric shock like pain; Gabapentin belongs to a group of medicines called anticonvulsants and can also be used to treat epilepsy A Cochrane systematic review of 37 studies (n = 5914) that assessed the analgesic efficacy of gabapentin in chronic neuropathic pain in adults concluded that gabapentin at doses of 1800 mg to 3600 mg daily can provide good levels of pain relief to some people with postherpetic neuralgia (PHN) and peripheral diabetic neuropathy, although Read about how gabapentin treats epilepsy and nerve pain and how to take it. NHS medicines information on gabapentin – what it's used for, side effects, dosage, and who can take it. • Chronic spinal problems e.g. sciatica, neck pain, low back pain • Underlying malignancy or other occult disease Consider referring patient to specialist setting if: • The patient is experiencing severe pain. • Neuropathic pain is significantly limiting participation in daily activities (including self-care, Neuropathic pain is different from pain caused by, for example, a pulled muscle or a sprain. It can be caused by conditions such as diabetes, shingles and trigeminal neuralgia (which affects the face). A common cause is a trapped nerve, for example, in the back or neck. It NICE has published an update to NG59 Low Back Pain and Sciatica. The updated guideline advises healthcare professionals NOT to offer benzodiazepines, gabapentinoids or opioids for sciatica. This extends advice in the original 2016 guideline to avoid gabapentinoids and routine use of opioids for low back pain. With nerve pain, it's thought to block pain by affecting the pain messages travelling through the brain and down the spine. Gabapentin is available on prescription. It comes as tablets, capsules and a liquid that you swallow. However, gabapentin is recommended by NICE as a first-line treatment option for adults with all types of neuropathic pain (except trigeminal neuralgia). There are no clinically relevant pharmacokinetic interactions between gabapentin and pregabalin. SPINAL Neuropathic Pain Initial presentation of low back pain WITH Public Health England guidance PHE-NHS England Pregabalin and Gabapentin Advice 5Dec 2014 Gabapentin is used to help reduce pain. It is especially good for nerve pain, such as burning, shooting, stabbing, pins and needles, crawling, electric shock like pain. How does it work? Gabapentin works by changing the way that nerves send messages to your brain. If the messages are reduced, then the pain will be reduced . Although gabapentinoids are commonly prescribed for non-neuropathic pain syndromes there is little evidence to support this practice, and prescribers should consider other interventions more likely to help, such as physical rehabilitation for back pain and musculoskeletal pain. NHS medicines information on dosage for gabapentin, how to take it and what to do if you miss a dose or take too much. Chronic pain is usually not a sign of on-going tissue damage but may relate to changes in the peripheral and central nervous system that occur over time so that the pain signalling becomes self-sustaining over a prolonged period. Common types of chronic pain include low back pain, pain related to arthritis and pain related
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