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If your doctor or health visitor says your baby is healthy, you can take gabapentin while breastfeeding. It's important to keep taking gabapentin to keep you well. Gabapentin passes into breast milk in small amounts. It has not been known to cause any side effects in breastfed babies. The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Gabapentin is a medication that has been used to prevent and control partial seizures, treat some forms of nerve pain, and treat moderate-to-severe restless legs syndrome. Some brand names are Horizant®, Gralise® and Neurontin®. In one study of nine mothers taking primidone, their infants' phenobarbital plasma levels were 37% of their mothers' plasma levels. Both of these drugs have caused sedation and poor nursing in breastfed infants. Neonatal withdrawal syndromes including convulsions have also been reported after abrupt discontinuation of breastfeeding. Here’s a breakdown of the guidelines and warnings for breastfeeding mothers taking gabapentin: 1. Gabapentin Transfer to Breast Milk. Gabapentin does pass into breast milk, but typically in low concentrations. Studies suggest that the levels of gabapentin in breast milk are relatively low, ranging from about 1% to 5% of the maternal dose Gabapentinoids are medicines used to treat seizures and nerve pain. Gabapentinoids include gabapentin (Neurontin) and pregabalin (Lyrica). These medicines also may be used to treat ongoing pain or pain after procedures. Gabapentinoids are considered safe to use while breastfeeding. An infant whose mother was taking gabapentin 36.7 mg/kg daily breastfed her infant 6 to 7 times daily for most of the first 1.6 months of life with some additional artificial feeding at night. The mother was also taking amitriptyline 2.5 mg daily. Can Breastfeeding Women Take Gabapentin? Gabapentin is excreted into the breast milk in women. It is believed that the nursing infant may be exposed to a maximum dose of approximately 1 mg/kg per day of gabapentin. Advocacy for breastfeeding has led to increased breastfeeding rates worldwide; however, more than 50 percent of breastfeeding women take some sort of drug, and data on excretion of drugs into Gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring. Published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily. With maternal doses up to 2.1 g/day, estimated doses for fully breastfed infants are 0.2 to 1.3 mg/kg/day (equivalent to 1.3 to 3.8% of the maternal weight-adjusted dose). An expert panel has deemed this drug is an acceptable choice for refractory restless leg syndrome during lactation. pain are amitriptyline, gabapentin and pregabalin. Amitriptyline Amitriptyline has been used for many years even in breastfeeding women as an antidepressant as well as to treat neuropathic pain. Mothers taking amitriptyline should be counselled to take care with co-sleeping as their natural responses will be altered. Purpose. Pain in the postpartum period is common and considered by many individuals to be both problematic and persistent 1.Pain can interfere with individuals’ ability to care for themselves and their infants, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain 2. Breastfeeding while taking gabapentin: Gabapentin enters breastmilk in low levels. Blood tests on breastfed infants found low levels or levels too low to be detected. Breastfeeding while taking gabapentin: Gabapentin enters breastmilk in low levels. Blood tests on breastfed infants found low levels or levels too low to be detected. There are reports of infants exposed to gabapentin through breastmilk; no side effects were noted. A single oral dose of either 300 mg or 600 mg given to the mother before cesarean section appeared to have no effect on breastfeeding initiation. An expert consensus guideline indicates that gabapentin is an acceptable choice for refractory restless leg syndrome during lactation. This practice allows mothers to manage their pain effectively while ensuring their babies receive minimal medication exposure through breast milk. Factors Influencing Medication Safety During Breastfeeding. Several factors influence how medications affect breastfeeding: Dose: Higher doses may result in higher concentrations in breast milk. Gabapentinand breastfeeding. gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring (1) published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily Nevertheless, in mothers suffering from epilepsy or bipolar disorders treated with antiepileptic drugs (AEDs), some concerns on infant health may raise. The decision to encourage breastfeeding in those women should be taken after a careful evaluation of the possible side-effects on the infant caused by the indirect exposure to AEDs via breast milk.
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