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Chronic gingivostomatitis (CGS) in the cat is a very painful disease, characterized by severe inflammation of the gingiva, buccal mucosa, and caudal oral mucosa. 1 CGS affects 0.7% to 10% of the general cat population. 2 Gabapentin is a medication used to treat pain in cats. It is also used as a sedative to help reduce anxiety during stressful situations, like car travel and vet visits. Here’s what you need to know about this common feline medication. Gabapentin is used in cats to treat chronic pain, especially of neuropathic origin and anxiety. For pain, this drug seems to be most effective when combined with other types of analgesics (for Gabapentin Anticonvulsant • 5–10 mg/kg PO Q 8–12 H Prednisolone Glucocorticoid• 0.5–1 mg/kg PO Q 24 H *Use of meloxicam oral suspension in cats is extra-label; †Approved for short-term use in cat≥.5 lb (2.5 kg) an≥ 6 months of age; §ISFM/AAFP Guidelines recommend administration up to 6 days Key Takeaways. Veterinarians commonly prescribe gabapentin to treat pain, seizures, and anxiety in dogs. Gabapentin is a human medication, and its use in veterinary medicine is “off-label,” meaning it is not FDA-approved for pets. Gabapentin is very effective as a pharmacologic element of multimodal analgesia in patients with chronic pain. The recommended dose for cats and dogs starts at 2 to 10 mg/kg PO q8–12h and may be increased to 50 mg/kg PO q8gh. 8 The veterinarian should re-evaluate patients every 5 to 7 days for potential dose increases. Gabapentin has many useful properties for treating cats beyond use as an anticonvulsant. It is used off-label in cats to reduce situational anxiety, provide pain relief, and is the preferred treatment for a condition called feline hyperesthesia syndrome. Feline idiopathic cystitis, also known as feline interstitial cystitis or FIC for short, is a type of feline lower urinary tract disease that causes inflammation of the bladder in cats. “Idiopathic” means that the cause of the disease process is unknown; “interstitial” refers to the location of the inflammation in the interstitium In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. Gabapentin, often combined with other analgesic and anti-inflammatory drugs (NSAIDs), is incredibly efficient in treating neuropathic pain in cats. It's also prescribed to relieve pain associated with cancer and arthritis. Veterinarians often prescribe it to cats for managing seizures or chronic pain related to nerve inflammation or cancer. While gabapentin has some anti-seizure properties, it is generally not the first choice for treating seizures in cats. The drug has been shown to be especially efficient in treating neuropathic pain in cats, usually in conjunction with other analgesic agents like nonsteroidal anti-inflammatory drugs (NSAIDs). Gabapentin is also prescribed for pain associated with malignancy and chronic arthritic pain in cats. While Gabapentin is not classified as a traditional anti-inflammatory drug like NSAIDs (nonsteroidal anti-inflammatory drugs), some studies suggest that it may have anti-inflammatory properties. These properties are believed to be related to its ability to modulate certain neurotransmitters and reduce the release of pro-inflammatory substances Gabapentin is used in cats to manage chronic pain, control seizures, and reduce anxiety, especially during vet visits. The dosage varies, typically ranging from 1.5 to 5 mg per pound for pain relief, 2.5 to 5 mg per pound for seizures, and 20 mg/kg for anxiety before vet visits. Gabapentin, while very few studies have been performed on its long-term use in cats, has thus far seemed safe and effective. In humans, Gabapentin is within the class of medications used to help prevent seizures (anticonvulsants) and is commonly prescribed for neuropathic pain. Several case reports note analgesia when gabapentin was used for treatment of chronic pain. 14,15 And in a clinical study on postoperative pain in dogs undergoing mastectomy, although pain scores did not differ, dogs receiving NSAIDs plus gabapentin required fewer opioid rescue doses than dogs receiving NSAIDs alone; thus, the gabapentin did Gabapentin is a commonly prescribed adjunctive therapy for cats with idiopathic refractory epilepsy. Gabapentin’s unique working mechanism and effects are often described as “promising.” Gabapentin for Chronic Pain in Cats. Because of the analgesia effects, Gabapentin is used to manage a cat’s chronic pain. Gabapentin for dogs is commonly prescribed for pain, anxiety, or seizures. It's generally safe, but there are some known side effects to be aware of. Over the counter pain medications for cats are designed to provide relief from mild to moderate pain, inflammation, and fever. These medications can be useful for short-term pain management, such as after surgery or in cases of arthritis.
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