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Gabapentin to treat numbness, tingling and nerve pain (neuropathic pain) Below you will find a summary about a medication used very often in the medical field to treat a variety of pain conditions- gabapentin, but with information specific to treating neuropathic pain in diabetes. Numbness and tingling is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lyrica, and have Multiple sclerosis. How much Gabapentin are you taking daily? You're right, there aren't any cures for the numbness, and gabapentin can only dull the pain, which is also not curable. I'm taking 3600 mg a day for the pain and numbness in my feet, and it's not working very well. Started taking Gabapentin less than three weeks ago for knee pain and foot numbness due to sciatica. Started waking in the morning with severe arm and shoulder muscle pain and weakness. At first blamed my mattress but it just kept getting worse. Told my GP and he told me to cut down to one pill at night for a week then stop taking it. Tingling or numbness in the extremities refers to abnormal sensations in the arms, hands, legs, or feet that may feel like pins and needles, burning, or a loss of sensation. Description of Tingling or Numbness in the Extremities. Tingling or numbness in the extremities is medically known as “paresthesia.” Millions of people suffer from the burning, tingling, and numbness of a form of neuropathy called idiopathic sensory polyneuropathy. A recent study directly comparing four medications produced disappointing results, but is a step in the right direction. The way gabapentin alleviates numbness is tied closely to its ability to dampen nerve excitability. By inhibiting certain calcium channels on neurons, gabapentin reduces the release of excitatory neurotransmitters that can cause heightened sensitivity and pain perception. Medicines such as gabapentin (Gralise, Neurontin, Horizant) and pregabalin (Lyrica), developed to treat epilepsy, often improve nerve pain. Side effects can include drowsiness and dizziness. Topical treatments. Lidocaine cream that is available without a prescription can be applied to the skin. Researchers aren’t quite sure how gabapentin works to treat numbness and muscle twitching in MS. A few studies have looked at gabapentin for treating muscle spasms in MS, and they found that it significantly improved spasticity (muscle stiffness and pain) compared to a placebo (inactive drug). I hate drugs. I ask for the lowest dose I am taking gabapentin 300 mg and duloxtene 20mg and alive or aspirin. I think statins are the reason I have to use a walker. numbness in lower and pain in upper legs. I started taking gabapentin for peripheral neuropathy almost a month ago. Over the last week my legs often go completely numb from the knee down. I can only assume it is the gabapentin. Has anyone else had this happen? Is it normal? Another extended-release form of gabapentin is FDA-approved to treat restless legs syndrome. This condition causes unpleasant or uncomfortable sensations in the legs and an irresistible urge to move them around, especially at night, which disrupts sleep. Gabapentin is the only thing that helps the pain but it will do nothing for the numbness. Even Lyrica can't do that. I also take 9mg time release dilaudid 2 x a day and 2 mg dilaudid 2 to 4 times a day depending on pain. my legs also reacted badly with gabapentin, but when I lowered the dose I was prescribed (900 mg a day!), it eased up significantly. Instead of three doses, I took one 300 mg dose. It gave me moderate help, but I did not like the brain fog or how it changed my gait. I’ve not taken Lyrica, but Gabapentin made the initial stages of my herniated disc survivable. My nerve is impinged on the S1 root, so I had rough numbness (leg and foot) and some loss of tendon and calf flexion. Diabetic neuropathy is a complication of diabetes that may affect your legs, causing numbness, tingling, and pain. including gabapentin and pregabalin, may also help relieve nerve pain The best medicine for numbness in feet depends on the cause, but Gabapentin is commonly prescribed to manage nerve pain and numbness, especially in cases like diabetic neuropathy. It helps stabilize nerve activity and reduce pain signals. I developed tingling in both my legs and right arm after a traumatic event. I have had it for over three years now and wonder if anyone else has had it this long. My legs can't get cold as then they hurt. I have been taking 300mg 3 times a day and wonder if it even helps. This disease has caused electrical sparks through my feet and legs, numbness in my toes and balls of the feet, cramping, a hard wooden-like swelling in the balls of the feet that makes it so I can't walk flat foot anymore. Gabapentin is a common medication-related cause of peripheral edema. This is when you experience swollen tissues in the body, often in the arms and legs. Up to 8% of people report edema with gabapentin clinical studies. But it’s more likely to occur in older adults. It’s also more likely with higher gabapentin dosages (greater than 1,800 mg).

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