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Gabapentin is fairly safe when you use it correctly. It does come with some possible side effects, though. People who misuse this drug are also at risk of additional side effects. Gabapentin is High doses of gabapentin can pose significant risks to health. As gabapentin becomes more widely prescribed, understanding its potential side effects is crucial. While this medication is often used to manage nerve pain and seizures, misuse and overdose can lead to severe consequences. I don’t often see doses as high as you are taking, but they are certainly used. In a seminal trial on pain following shingles (post-herpetic neuralgia), the target dose of gabapentin was 900 mg Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. While less common, the most serious side effects of gabapentin are described below, along with what to do if they happen. Severe Allergic Reactions. Gabapentin can cause allergic reactions, Rare but serious gabapentin side effects include mood changes in children. It can also cause suicidal thoughts or behaviors in children and adults. If you or your child experience changes in behavior or mood while taking gabapentin, contact your prescriber immediately. Box 1: Gabapentin doses and adverse effects 6, 7. Low dose is defined as < 900 mg, moderate dose as 900–1799 mg and high dose as > 1800 mg. Gabapentin’s exact mode of action is unknown. It is structurally similar to GABA but does not directly bind to GABA receptors. High-dose gabapentin is associated with a twofold increase in adverse I cracked 2 ribs. About a week later the whole side of my leg went numb from hip to foot. There is still some numbness there. I tried to cut back on gabapentin. Just cutting midday dose to 300mg and taking 600mg other 2x caused what felt like sparklers going of under the skin of my thigh multiple times a day. Side Effects Common side effects of gabapentin. Gabapentin can cause several common side effects, including dizziness, drowsiness, and fatigue. Other commonly reported side effects include headache, nausea, and blurred vision. These side effects are usually mild and tend to improve over time as the body adjusts to the medication. Avoid driving or hazardous activity until you know how gabapentin will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Do not stop using gabapentin suddenly, even if you feel fine. You should not take gabapentin if you are allergic to it. One of my patients has to have his mom drive him because of low energy and sleepiness side effects he gets from gabapentin. I'm not a psychiatrist, just a TMS tech, but most of our onsite MDs and psychiatrists recommend weaning off it if it is possible to reduce the risk of treatment not being as effective as it could be. Memory loss and other cognitive adverse effects are well known to occur with gabapentin (brand name Neurontin) and they appear to be dose related, meaning higher doses result in a higher incidence rate. In your situation, your dose far exceeds the maximum recommended daily dose, which is 3,600mg (given as divided doses throughout the day). Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Common side effects of gabapentin include: flulike symptoms such as fever or body aches. Rare but serious side effects of gabapentin include: changes in memory, ability to concentrate, or personality. Gabapentin may cause breathing problems in people who use opioid pain medicines and those with chronic obstructive pulmonary disease (COPD). But researchers found that opioid abusers used gabapentin to reinforce the effects of heroin. Evidence showed that people who abused opioids were adding gabapentin to increase their high. A 2017 study in the journal Addiction concluded that combining opioids with gabapentin or pregabalin could increase the risk of overdose deaths. The study I don’t often see doses as high as you are taking, but they are certainly used. In a seminal trial on pain following shingles (post-herpetic neuralgia), the target dose of gabapentin was 900 mg • The most common side effects of gabapentin tablets include: [sideeffects] Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of gabapentin tablets. For more information, ask your healthcare provider or pharmacist. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. If you miss a dose of gabapentin‚ take it as soon as you remember. However‚ if it is almost time for your next dose‚ skip the missed dose and take your next dose at the regular time. Do not take two doses of gabapentin at the same time. Gabapentin can cause side effects‚ such as dizziness‚ drowsiness‚ and nausea. Side Effects, Uses, Dosage, and More About Gabapentin Oral Capsules Medically reviewed by Philip Ngo, PharmD — Written by University of Illinois — Updated on February 13, 2024 Side effects
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