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There are 4 disease interactions with gabapentin. Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. What Drugs Should Not Be Taken With Gabapentin? Gabapentin, commonly known by the brand name Neurontin, is a medication primarily used to manage seizures, nerve pain, and restless legs syndrome. While it can be highly effective, it’s crucial to understand its potential interactions with other substances. Patients should be informed of the potentially fatal risks of interactions between gabapentin and alcohol, and with other medicines that cause CNS depression, particularly opioids. MHRA/CHM advice: Antiepileptic drugs in pregnancy: updated advice following comprehensive safety review (January 2021) Medicines that interact with gabapentin may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with gabapentin. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. You can also use the Drugs.com Drug Interaction Checker to learn more. This tool explains what the interaction is, how it occurs, the level of importance and how to handle the drug interaction. It will also display any interactions between your chosen drugs, food, beverages, or a medical condition. Taking gabapentin together with other medications can lead to drug interactions. Some of the drugs that can potentially interact with gabapentin include: Naproxen. Studies suggest that naproxen (aleve) increases the amount of gabapentin absorbed in the body. Comprehensive alcohol & food interactions for gabapentin. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. There are a number of drugs that should not be taken with gabapentin, including certain antibiotics, antifungal medications, and drugs used to treat seizures. In some cases, taking these drugs with gabapentin can increase the risk of side effects or make the gabapentin less effective. There are 4 disease interactions with Neurontin (gabapentin). Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. What other drugs will affect gabapentin? Taking gabapentin with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Gabapentin, like any other substance, can interact with other substances.Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Several medications can interact negatively with gabapentin, leading to increased side effects or reduced effectiveness. Gabapentin is a medication often prescribed for nerve pain, seizures, and certain anxiety disorders. Does gabapentin interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults and the pain of postherpetic neuralgia. Learn about side effects, drug interactions, dosages, warnings, and more. Both Gabapentin and Doxepin have effects on the CNS and can cause sedation, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing). In some cases, use of two or more drugs that have effects on the CNS might also increase the risk of CNS depressant effects (which could range from sedation to Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. In general, some studies have shown that gabapentin is an antiepileptic drug with a low profile of interaction with other drugs. 68, 69 Specifically, a general review stated that gabapentin lacks interactions with hepatic enzymes, plasma proteins and other drugs; these factors make gabapentin suitable for elderly patients suffering from hepatic Do not use more than the recommended dose of gabapentin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
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