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Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. Gabapentin, a medication primarily used to treat seizures and nerve pain, is generally considered safe when used as directed. However, like many medications, it can interact negatively with other substances, leading to unwanted side effects or reduced efficacy. 7. Interactions. Medicines that interact with gabapentin may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with gabapentin. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Several medications can interact negatively with gabapentin, leading to increased side effects or reduced effectiveness. Gabapentin is a medication often prescribed for nerve pain, seizures, and certain anxiety disorders. Gabapentin has the following interaction information: Severe interactions are highlighted with a red marker. Both Gabapentin and Agomelatine have effects on the CNS and can cause sedation, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing). 270 medications are known to interact with gabapentin. Includes: drug, food, pregnancy, breastfeeding and therapeutic duplication warnings. Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults, treating the pain of post herpetic neuralgia. Gabapentin belongs to a class of drugs known as anti- seizure drugs. Take gabapentin by mouth as directed by your doctor, usually once a day with the evening meal. There are 4 disease interactions with gabapentin. Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Gabapentin, like any other substance, can interact with other substances. Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Are there any serious interactions with gabapentin and other medications? Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Some examples include narcotic opioids, anti-anxiety medicines, antidepressants, and antihistamines. Taking gabapentin together with other medications can lead to drug interactions. Some of the drugs that can potentially interact with gabapentin include: Naproxen. Studies suggest that naproxen (aleve) increases the amount of gabapentin absorbed in the body. In general, some studies have shown that gabapentin is an antiepileptic drug with a low profile of interaction with other drugs. 68, 69 Specifically, a general review stated that gabapentin lacks interactions with hepatic enzymes, plasma proteins and other drugs; these factors make gabapentin suitable for elderly patients suffering from hepatic Gabapentin drug interactions. There are 270 drug interactions with gabapentin. Gabapentin disease interactions. There are 4 disease interactions with gabapentin which include: drug dependence; renal dysfunction; suicidal tendency; hemodialysis There are 270 drug interactions with Neurontin (gabapentin). Neurontin alcohol/food interactions There is 1 alcohol/food interaction with Neurontin (gabapentin). Does gabapentin interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. When it comes to drug interactions, some might cause harmful side effects, while others can impact gabapentin’s effectiveness. Gabapentin belongs to a group of medications called anti-epileptics . It can be used to treat seizures and nerve pain associated with shingles . Gabapentin is primarily eliminated from the body through the kidneys. When taken with other drugs that also interact with the kidneys, gabapentin can increase the risk of kidney damage or other serious side effects. It is important to talk to a doctor before combining gabapentin with any other medication.
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