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Neurontin (gabapentin), generally prescribed for the treatment of nerve pain, is sometimes used to relieve severe pain caused by knee osteoarthritis (OA). Osteoarthritis, also known, as wear-and-tear arthritis, can often become so severe that joint replacement surgery is needed. Medications are a common reason for swollen ankles and feet, also called pedal edema. Amlodipine (Norvasc), gabapentin (Neurontin, Horizant, Gralise), and pregabalin (Lyrica) can cause puffy legs and ankles. Birth control pills, certain over-the-counter pain medications, and steroids are a few other culprits. Background. Gabapentin binds to the alpha-2-delta subunit of presynaptic voltage-gated calcium channels and is used for a wide variety of indications both Food and Drug Administration approved and off-label. 1-3 It is approved by the Food and Drug Administration to treat postherpetic neuralgia and epilepsy 4 with common off-label indications including fibromyalgia, anxiety, mood disorders, and Summary: Joint swelling is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Humira, and have Rheumatoid arthritis. I have swelling in my legs caused by lymphedema and have to wear compression socks but mine was not caused by a medication. I also would be concerned if it's been over 5 months since stopping gabapentin and the swelling and pain is still in the hands and feet. Sorry to say, but my swelling lead to weight gain.I was prescribed Gabapentin for nerve pain. I started at 200 mgs once daily at bedtime. I couldn't stay on it for longer than two weeks. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Managing gabapentin-induced edema requires a multi-faceted approach, considering both lifestyle modifications and potential medication adjustments. Our article will provide practical tips and strategies that can help alleviate and manage the swelling effectively. Gabapentin (generic for Neurontin), is commonly prescribed for neuropathy. Neuropathy is pain felt along the nerve endings. Many diabetics suffer from neuropathy. Gabapentin is also an anti seizure med. 300 mg at bedtime is a small dosage but sleepiness is a common side effect of the medicine so at the very least it may help promote sleep. I get swelling below the knee, closer to my ankle. I just wear socks that have a loose neck or just roll them down below the swelling. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system. It is not used for routine pain caused by minor injuries or arthritis. Gabapentin is an anticonvulsant. Gabapentin was discontinued and his lower extremity swelling improved over subsequent days. Incidence of pedal edema with gabapentin use is approximately 7 to 7.5% with all studies being in elderly patients receiving doses above 1200 mg/day. Seven days after the administration of the gabapentin, the patient complained from pain and edema and scaling and hyperesthesia in his lower extremities and pitting edema, pain and tenderness. Gabapentin can cause edema: This medication may lead to swelling in some users. Dosage matters : Higher doses of gabapentin can increase the risk of edema. Monitor side effects : Regular checks for swelling are crucial during treatment. Swelling from gabapentin typically lasts a few days to weeks, depending on individual factors and dosage. Gabapentin, a medication primarily used to treat nerve pain and seizures, has gained attention for its effectiveness in managing various conditions. However, like any medication, it can come with side effects. First case of Covid in May 2023. It was accompanied by pneumonia and strep throat and I tested positive for 18 days in July while walking my dog I pulled a muscle in my left calf going up a slight incline, just radiated into my left knee with some swelling and nerve pain, I’ve been prescribed gabapentin for restless leg and take 300 mg at night. Although gabapentin is generally well tolerated, 1 potential reported adverse effect is peripheral edema. However, due to the extensive number of etiologies of peripheral edema, medication causes may be overlooked on an inpatient psychiatric unit. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Joint and muscle pain from Lyrica are usually mild and goes away over time. But if your joint pain is severe or isn’t improving, let your prescriber know. In some cases, they may recommend switching you to a medication closely related to pregabalin called gabapentin (Neurontin). Gabapentin isn’t known to cause muscle or joint pain.
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