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Drug Interactions: A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) 10 minor drug interactions (52 brand and generic names) A total of 722 drugs are known to interact with Lithium: Lithium, gabapentin, sulpiride and amisulpride are predominantly renally excreted and so are not likely to interact with warfarin. Conclusion: Many psychotropics are involved in predictable interactions with warfarin. Drugs with a known low interaction potential should be chosen instead of those known or predicted to interact. Europe PMC is an archive of life sciences journal literature. The study uses data from the FDA. It is based on lithium carbonate and gabapentin (the active ingredients of Lithium carbonate and Gabapentin, respectively), and Lithium carbonate and Gabapentin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Using lithium together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. 722 medications are known to interact with lithium. Includes amlodipine, gabapentin, lisinopril. Evidence-based interaction details between Gabapentin (brand name (s): Neurontin, Gralise) and Lithium, including interaction severity and how likely the interaction is to occur. Lithium and gabapentin. Gabapentin is currently being studied as a treatment for bipolar disorder, and there have been favorable reports regarding its potential as a mood stabilizer (82, 83). The advantages of gabapentin include the lack of interactions with other drugs in the cytochrome P450 system and the lack of protein binding . Since there Lithium (Li) and gabapentin are both exclusively eliminated by renal excretion. When used in combination, a competitive drug-drug interaction could possibly alter Li renal excretion with important clinical implications considering the rather narrow therapeutic index of Li. Gabapentin patients contributed 915.8 person-years (PY) of follow-up time; lithium patients contributed 1421.3 PY. There were 21 suicide/self-harm events in the gabapentin group and 16 in the lithium group. Unadjusted incidence rates were 22.9 and 11.3/1000 PY in the gabapentin and lithium groups, respectively (P=0.03). No interactions between gabapentin and valproate, carbamazepine or lithium have been reported. Does gabapentin interact with any other prescriptions or over-the-counter medications, such as MAO It's a pretty low dose of gabapentin, which I've found is a great mediator for mood swings and just general well-being. There have been times in the past where I've had issues with the lithium. The most prominent one being for a while, I wasn't sure I could be certain I was really alive. When a medication works right, it boosts your health or helps you feel better. But a drug can bring on problems if it doesn't mix well with something else you put into your body, like another Fortunately, many lithium interactions can be managed by monitoring your blood work. If needed, your dose can be adjusted. But there are still several important interactions that you should know about. Use the interactions A to Z to look up a drug and see which other drugs it interacts with and the severity of these interactions. This unique pathway means that drugs affecting kidney function or those that also have renal excretion could significantly interact with gabapentin. Common Medications That Interact with Gabapentin. Certain classes of medications pose risks when taken alongside gabapentin. Understanding these interactions helps mitigate potential side effects Currently, the most useful mood stabilizer combinations are the mixtures of anticonvulsants and lithium, particularly valproate plus lithium. Carbamazepine, lamotrigine, and gabapentin have also been added to lithium with apparent safety. Fanapt Interactions. There are 676 drugs known to interact with Fanapt (iloperidone), along with 14 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 262 are major, 411 are moderate, and 3 are minor. The advantages of gabapentin include the lack of interactions with other drugs in the cytochrome P450 system and the lack of protein binding. Since there is little risk of drug interactions, use with lithium is likely to be safe. Using lithium together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.
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