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(decreased gabapentin bioavailability)- aluminum and magnesium containing antacids; (increased CNS depression)- CNS depressants dosages (adults)- initial 300mg on day 1, increased to 300mg BID on D2, increased to 300mg TID on D3, and increased gradually thereafter according to pain response, up to 600mg TID (1800mg maximum) gabapentin (ga-ba- pen -tin) Neurontin. Therapeutic: analgesic adjuncts, therapeutic, anticonvulsants, mood stabilizers. Partial seizures (adjunct treatment). Postherpetic neuralgia. Unlabeled Use: Chronic pain. Prevention of migraine headache. Bipolar disorder. Anxiety. Mechanism of action is not known. Indications Adjunctive therapy in the treatment of partial seizures with and without secondary generalization in adults and children 3–12 yr with epilepsy Orphan drug use: Treatment of amyotrophic lateral sclerosis Nursing Considerations Therapeutic Effects Side/Adverse Effects; Anticonvulsant: gabapentin: Administer first dose at bedtime to decrease dizziness and drowsiness Monitor for worsening depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior Taper dose; do not stop abruptly: Decreased neuropathic pain or seizures Indications. Gabapentin is an anticonvulsive medication that was first discovered in the 1970s. The medication received approval from the US Food and Drug Administration (FDA) in 1993 and has been available in generic form in the USA since 2004. Gabapentin was originally used as a muscle relaxant and an anti-spasmodic. Indications for use: Adjunctive treatment for seizure control, postherpetic neuralgia, moderate to severe primary restless legs syndrome. Off-label uses include bipolar disorder , migraine prophylaxis, tremor associated with multiple sclerosis , neuropathic pain, diabetic peripheral neuropathy, vasomotor symptoms (hot flashes), fibromyalgia Gabapentin is one of the top 100 drugs prescribed in the US, so there’s a very good chance it will show up on NCLEX or your nursing school exams. Let’s go through the key things you need to know about this medication using the Straight A Nursing DRRUGS framework. Generic Name Gabapentin DrugBank Accession Number DB00996 Background. Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. 8 Understanding proper nursing considerations is crucial for safe and effective patient care. Generic name: Gabapentin. Brand names: Neurontin, Gralise, Horizant, Gabarone. Pharmacologic class: Anticonvulsant, Antiepileptic. Therapeutic class: Anticonvulsant, Analgesic for neuropathic pain. Find information on Gabapentin (Gralise, Horizant) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. Identify appropriate indications for use of gabapentin. Relate general characteristics of gabapentin to specific patient situations. Apply nursing process considerations for gabapentin to specific patient situations. Correctly calculate dosage for gabapentin. You’ve learned about gabapentin (Neurontin) nursing implications (aka nursing considerations) and patient teachings in this article. In addition, you’ve learned about gabapentin’s mechanism of action, pharmacokinetics, dosage, indications, contraindications, side effects, nursing assessment, and nursing interventions. Generic Name. Gabapentin. Trade Name. Neurontin. Indication. Seizures, peripheral neuropathy, neuropathic pain, prevention of migraines. Action. Exact method of action unknown, may play a role in stabilizing neural membranes Gabapentin is an anticonvulsive medication that received approval from the US Food and Drug Administration (FDA) in 1993 and has been available in generic form in the USA since 2004. Gabapentin was originally used as a muscle relaxant and an anti-spasmodic. However, it was later discovered that gabapentin has the potential of an anticonvulsive medication and can be used as an adjunct to more Nursing Considerations for Gabapentin. When administering or caring for patients taking gabapentin, nurses should consider several important factors. Nursing Assessment. 1. Assess the patient’s medical history, including any known allergies, previous adverse reactions to gabapentin or similar medications, and relevant medical conditions. Generic Name. Gabapentin. Trade Name. Neurontin. Indication. Seizures, peripheral neuropathy, neuropathic pain, prevention of migraines. Action. Exact method of action unknown, may play a role in stabilizing neural membranes Advise patient not to take gabapentin within 2 hr of an antacid. Gabapentin may cause dizziness and drowsiness. Caution patient to avoid driving or activities requiring alertness until response to medication is known. Seizure patients should not resume driving until physician gives clearance based on control of seizure disorder. Gabapentin is a GABA neurotransmitter analog; however, it does not inhibit GABA uptake or degradation. It appears to interact with GABA cotical neurons, but its relationship to functional activity as an anti convulsant is unknown. Used in conjunction with other anticonvulsants to control certain types of seizures in patients with epilepsy. Understanding gabapentin's indications, mechanisms, and potential complications helps nurses provide comprehensive care and improve patient outcomes. Never stop taking gabapentin without talking to your healthcare provider first. Stopping gabapentin suddenly can cause serious problems, including increasing your risk of seizures (if you are taking gabapentin to control seizures) or not improving your symptoms (if taking gabapentin for other indications).
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