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Gabapentin, also known by the brand name Neurontin, is an anticonvulsant medication primarily used to treat seizures and manage neuropathic pain. It is a synthetic medication that works by regulating certain neurotransmitters in the brain. What is Gabapentin? Gabapentin is generally safe and non-toxic, although there have been several published case reports of adverse effects with gabapentin including severe myopathy, severe myoclonus, neutropenia, hypoglycaemia episodes and altered consciousness. 3 The recommended dose of gabapentin in patients with creatinine clearance >60 ml/min is 1200 mg/day Gabapentin Increasingly Implicated in Overdose Deaths If an individual suspects a gabapentin overdose or observes someone experiencing symptoms of overdose, it is essential to call emergency services or the local poison control center immediately. Medical professionals are equipped to provide guidance and assistance in such situations. How Much Gabapentin to Overdose? The lethal dose of gabapentin ranges from 49 grams or more. Gabapentin overdose side effects like ataxia, labored breathing, diarrhea, and sedation have been reported by the FDA in people who took 49 grams or more of the drug. A lower starting dose may be necessary to prevent overdose and accumulation of the drug in the body. Monitoring of kidney function is recommended. Gabapentin use in pediatric patients. Gabapentin is approved for use in children 3 years of age and older for certain indications٫ such as partial seizures. What Is the Gabapentin Withdrawal Timeline? It is difficult to anticipate what the timeline for gabapentin withdrawal will look like because it will vary greatly depending on several different factors, such as: Whether the gabapentin use was recreational or for medical purposes; How much gabapentin was consumed Gabapentin overdose can lead to various symptoms, highlighting the drug’s impact on the central nervous system and other bodily functions. Since overdose is a medical emergency, identifying its warning signs promptly is crucial for timely medical intervention. Recognizing the Signs of Gabapentin Overdose. As with any substance, it’s important to understand the general overdose symptoms — and the signs of a gabapentin overdose include unique characteristics: Shallow breathing, slowed down breathing, or difficulty taking a breath; Dizziness and lightheadedness; Confusion; Slurred speech; Drooping Key Takeaways Understanding Gabapentin: Uses and Effects Gabapentin, known by the brand names Neurontin, Gralise, and others, is a medication primarily used to treat seizures and neuropathic pain. It is often prescribed for managing postherpetic neuralgia in adults, which is pain following a shingles infection. Gabapentin has also found off-label use for a variety of [] When combined with a central nervous system depressant, a gabapentin overdose may cause respiratory depression and coma, potentially requiring artificial ventilation to ensure airflow. If you suspect a gabapentin overdose, call 911. Gabapentinoids are commonly ingested in self-harm attempts and often misused for their sedative and euphoric properties. These medications can cause lethargy or agitation in overdose, increase risk of death combined with opioids, and manifest a withdrawal syndrome. A gabapentin overdose is rare, but it is possible. The likelihood of an overdose increases when you abuse gabapentin with other drugs like opioids and alcohol. If you or someone you know is experiencing a gabapentin overdose, seek medical help immediately. Common symptoms of gabapentin overdose are drowsiness, fast heartbeat, dizziness, low blood pressure, nausea, vomiting, and impaired coordination. In severe cases, lethargy, coma, and death may occur. Research on people who died from drug overdose found that 22% had gabapentin in their system. This does not necessarily mean that gabapentin caused the overdose, but the drug is associated with one in five overdose deaths in the United States. Related: The Link Between Gabapentin and Suicide. Gabapentin Overdose Symptoms Gabapentin and Overdose Gabapentin overdose can occur when someone takes more gabapentin than prescribed or recommended. Gabapentin overdose can lead to a number of serious health problems‚ including⁚ Seizures; Coma; Respiratory depression; Death; Gabapentin overdose is treated with supportive care‚ such as⁚ Intravenous fluids; Oxygen In 2017, a study published in the journal Addiction noted that users who abuse heroin with gabapentin are at an increased risk of lethal overdose. 7 A pain and addiction specialist told the Louisville Courier-Journal that while gabapentin is unlikely to cause problems on its own, it could cause respiratory depression and death if mixed with opioids like illicit fentanyl and heroin. 8 Anyone who shows signs of an overdose or allergic reaction to gabapentin should contact emergency medical services immediately. Left untreated, these symptoms can turn fatal. As the rate of abuse increases, many wonder “Can you overdose on gabapentin?” Here, we’ll discuss whether and how gabapentin overdose can happen and what to expect if someone has taken too much gabapentin. Misusing gabapentin can lead to a fatal overdose, though the risk is much less if you take it as prescribed. However, unlike opioids, there is no antidote to reverse the overdose like naloxone. A gabapentin overdose is a medical emergency.
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