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There are 544 drugs known to interact with Nardil (phenelzine), along with 24 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 153 are major, 385 are moderate, and 6 are minor. Using phenelzine together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Adult Initially 15 mg 3 times a day, response is usually seen within first week; dose may be increased if necessary after 2 weeks if response is not evident, increased if necessary to 15 mg 4 times a day, doses up to 30 mg three times a day may be used in hospital patients; response may not become apparent for up to 4 weeks; once satisfactory response has been achieved, reduce dose gradually 544 medications are known to interact with phenelzine. Includes amlodipine, gabapentin, lisinopril. Phenelzine is used to treat certain types of depression. It belongs to the group of medicines called monoamine oxidase inhibitors (MAOI). This medicine works by blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system. Phenelzine, sold under the brand name Nardil among others, is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine family which is primarily used as an antidepressant and anxiolytic to treat depression and anxiety. [3] Medscape - Restless Leg Syndrome and postherpetic neuralgia dosing for Horizant (gabapentin enacarbil), adverse effects, comprehensive interactions, contraindications, pregnancy & lactation Do not use more than the recommended dose of gabapentin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns. Generally speaking, you need to avoid combining Gabapentin with substances that increase drowsiness, such as opioids, benzodiazepines, and alcohol. Also avoid some antacids, because they reduce the absorption of gabapentin into the bloodstream. Phenelzine controls the symptoms of depression but does not cure the condition. It may take 4 weeks or longer for you to feel the full benefit of phenelzine. Continue to take phenelzine even if you feel well. Do not stop taking phenelzine without talking to your doctor. Your doctor probably will want to decrease your dose gradually. Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. Drug-drug interactions: Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy. Consult drug interactions database for more detailed information. Special populations: Elderly: The MAO inhibitors are effective and generally well-tolerated by older Medscape - Indication-specific dosing for Nardil (phenelzine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost Description for Nardil. NARDIL ® (phenelzine sulfate) is a potent inhibitor of monoamine oxidase (MAO). Phenelzine sulfate is a hydrazine derivative. It has a molecular weight of 234.27 and is chemically described as C 8 H 12 N 2 • H 2 SO 4. Drug interactions are reported among people who take Phenelzine sulfate and Gabapentin. Common interactions include diplopia among females and drug ineffective among males. Phenelzine is a monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. More about phenelzine. Check interactions; Compare alternatives; Pricing & coupons; Reviews (157) Drug images; Side effects; During pregnancy; Drug class: monoamine oxidase inhibitors; Breastfeeding; En español; Patient resources. Phenelzine drug information; Phenelzine (Advanced Reading) Other brands. Nardil. Professional resources Additionally, you should avoid drinking alcohol as it can worsen the symptoms of depression while making the phenelzine side effects worse. Since phenelzine can make you tired, take care when driving a vehicle or operating machinery. Phenelzine interactions. Phenelzine, like other MAOIs, has a long list of potential interactions with other drugs. Does phenelzine interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal Phenelzine: side effects, dosage, interactions, FAQs, reviews. A dangerous drug interaction can occur between phenelzine and certain other medicines you use
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