In general, some studies have shown that gabapentin is an antiepileptic drug with a low profile of interaction with other drugs. 68, 69 Specifically, a general review stated that gabapentin lacks interactions with hepatic enzymes, plasma proteins and other drugs; these factors make gabapentin suitable for elderly patients suffering from hepatic Gabapentin and pregabalin are members of a class of anti-convulsive and anti-epileptic drugs called gabapentinoids. Gabapentin was first approved in 1993 and pregabalin followed in 2004. They’ve been widely prescribed to treat certain types of pain as well. Conditions gabapentin and pregabalin are approved to treat include: May interact with some other medications including antacids, hydrocodone, morphine, and other drugs that cause sedation or dizziness. Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults, treating the pain of post herpetic neuralgia. Gabapentin belongs to a class of drugs known as anti- seizure drugs. Take gabapentin by mouth as directed by your doctor, usually once a day with the evening meal. Does gabapentin interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, Gabapentin is ineffective in absence seizures and should be used in caution in patients with mixed seizure disorders involving absence seizures. Gabapentin has been associated with drug reaction with eosinophilia and systemic symptoms (DRESS), otherwise known as multi-organ hypersensitivity. There are 4 disease interactions with gabapentin. Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Neurontin (gabapentin) is an anti-eleptic medication used to treat seizures that occur with epilepsy, as well as nerve pain associated with shingles. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. There are 3 main types of drug interactions to watch for: Drug-drug interactions: This is the most common type of drug interaction and involves one drug interacting with another. If you take many medicines, your chances for this type of interaction increases. Gabapentin is a common prescription drug that is used to treat a variety of conditions, and it is important to understand the potential interactions with other drugs and what to avoid. In this article, we’ll discuss the drugs that should not be taken with gabapentin and any potential risks associated with them. Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. Are there any serious interactions with gabapentin and other medications? Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Some examples include narcotic opioids, anti-anxiety medicines, antidepressants, and antihistamines. Patients should be informed of the potentially fatal risks of interactions between gabapentin and alcohol, and with other medicines that cause CNS depression, particularly opioids. MHRA/CHM advice: Antiepileptic drugs in pregnancy: updated advice following comprehensive safety review (January 2021) Gabapentin drug interactions. There are 270 drug interactions with gabapentin. Gabapentin disease interactions. There are 4 disease interactions with gabapentin which include: drug dependence; renal dysfunction; suicidal tendency; hemodialysis Does gabapentin interact with my other drugs? Enter medications to view a detailed interaction report using our Drug Interaction Checker. 270 medications are known to interact with gabapentin. Includes: drug, food, pregnancy, breastfeeding and therapeutic duplication warnings. Understanding drug interactions is crucial when managing medications, especially when dealing with drugs like gabapentin. Gabapentin, often prescribed for nerve pain, seizures, and other conditions, can interact with a range of other medications, sometimes leading to adverse effects. It’s essential to be aware of these potential interactions Gabapentin, like any other substance, can interact with other substances. Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices.
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