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Common side effects include dizziness, drowsiness, fatigue, and coordination problems. These effects can increase the risk of falls and other accidents, posing a significant concern for elderly individuals already prone to mobility issues. Cognitive Effects. Another aspect to consider is the cognitive impact of Gabapentin on the elderly. Discover the potential side effects of gabapentin in elderly women, including common reactions, risks specific to older adults, and important considerations for safe use. However, elderly patients are more likely to have unwanted effects (eg, problems with balance or walking, swelling in the feet or legs) and age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving gabapentin. Along with causing dizziness, gabapentin can worsen your coordination. This can increase your risk of falls, which is especially dangerous for older adults. If you’re just starting to take gabapentin or your dose has increased, avoid driving or doing any activity that requires alertness. Confusion and impaired thinking are serious concerns with gabapentin use in older people. Gabapentin can further exacerbate existing cognitive issues, making it difficult for individuals to manage daily activities and potentially leading to distress for both the individual and their caregivers. Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Watch for breathing issues But in older adults, they can cause serious problems. Delirium, falls, and cognitive problems are just a few examples. Benzodiazepines (BZDs) should also be avoided for sleep problems. These include medications like estazolam, triazolam (Halcion), and temazepam (Restoril). They have the same risks as Z-drugs for older people. Older adults, for instance, may be more sensitive to the effects of gabapentin and may require lower doses. Similarly, individuals with kidney problems may need dose adjustments, as gabapentin is primarily excreted through the kidneys. Gabapentin for sleep in elderly patients is a topic that deserves special attention. If you or an elderly under your care take gabapentin and experiences fever, hives, a skin rash, swelling in the face or mouth, breathing problems, and swollen lymph nodes, it is important to stop using the drug and call your doctor immediately as it could be due to a hypersensitivity problem. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Medication Use in Older Adults. J Am Geriatr Soc. 2015 Nov;63(11):2227-46. 2Hanlon JT, Semla TP, Schmader KE. Alternative Medications for Medications in the Use of High-Risk Medications in the Elderly and Potentially Harmful Drug-Disease Interactions in the Elderly Quality Measures. J Am Geriatr Soc. 2015 Dec;63(12):e8-e18. Elderly patients often require lower doses of gabapentin due to age-related changes in kidney function. A study by Ahmed et al. (2017) found that gabapentin clearance in elderly nursing home patients was significantly lower than in younger adults, necessitating dose adjustments. 2.4.1. Peripheral Syndromes Post-Herpetic Neuralgia (PHN) The PHN is defined “pain continuing 90 days past the diagnosis of herpes zoster (HZ) or rash onset” [].The annual incidence of acute herpes zoster infection among healthy people under the age of 20 years is approximately 1 per 1000; the incidence is 5 to 10 times greater for those older than 80 years []. In addition to cognitive issues, mood swings and depression can occur. Some elderly patients may feel unusually irritable or withdrawn, which can affect their overall quality of life. Managing Gabapentin Side Effects. Successfully managing gabapentin side effects in elderly loved ones often involves a multi-faceted approach. Another option is gabapentin, which belongs to the same class of drugs as Lyrica but may have a different side effect profile. Understanding the gabapentin side effects in elderly patients can help determine if it’s a more suitable alternative. Gabapentin is often used to treat neuropathic pain and epilepsy, similar to Lyrica. Learn about the common side effects of gabapentin in elderly patients, including dizziness, fatigue, cognitive impairment, and more. Explore the connection between gabapentin and depression, mechanisms behind gabapentin-related depression, and strategies to manage and mitigate side effects. Gabapentin can be beneficial for many elderly patients, but it’s crucial to be aware of potentially serious side effects that require immediate medical attention. Recognizing these symptoms early can prevent complications and ensure prompt treatment. It may be reasonable to start older adults on a low dose of gabapentin, which can be effective to treat pain while exposing patients to a lower risk of adverse mental status side effects of gabapentin (dizziness, drowsiness and confusion). Gabapentin may cause breathing problems in people who use opioid pain medicines and those with chronic obstructive pulmonary disease (COPD). Older adults who take gabapentin also are at higher risk of breathing problems.
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