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This article explains what gabapentin is, its approved and off-label uses, and how the drug works to treat restless legs syndrome and other medical conditions. It also describes the possible side effects and risks and lists other drugs and treatments that may help ease RLS symptoms. Gabapentin (Neurontin, Gralise, Horizant) is a medicine used to treat partial seizures, nerve pain from shingles and restless leg syndrome. It works on the chemical messengers in your brain and nerves. Gabapentin is from a group of medicines called anticonvulsants. Medicines such as gabapentin, gabapentin enacarbil and pregabalin are the first line of treatment for most people with RLS. These medicines can cause side effects such as dizziness, unsteadiness, mental fog and weight gain. Medicines that increase dopamine in the brain. These medicines affect levels of the chemical messenger dopamine in the brain. Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Restless legs syndrome (RLS) is a common disorder. The population prevalence is 1.5% to 2.7% in a subgroup of patients having more severe RLS with symptoms occurring 2 or more times a week and causing at least moderate distress. It is important for primary care physicians to be familiar with the disorder and its management. Much has changed in the management of RLS since our previous revised It's not entirely clear how gabapentin works to treat restless legs syndrome. Common side effects of gabapentin include: flulike symptoms such as fever or body aches. Rare but serious side effects of gabapentin include: changes in memory, ability to concentrate, or personality. Gabapentin and pregabalin are also sometimes prescribed to help relieve painful symptoms of restless legs syndrome. Side effects of these medications include dizziness, tiredness and headaches. Medicines for aiding sleep. If restless legs syndrome is badly disrupting your sleep, a short-term course of medicine may be recommended to help you Restless legs syndrome (RLS) is a movement disorder that is described as an urge to move the legs or arms, commonly in response to an uncomfortable feeling. The urge to move has the following three features: • It is present at rest (sitting or lying down) • It is relieved (often only for a short time) by movement, especially walking Common Side Effects of Gabapentin. While gabapentin is generally well-tolerated, some individuals may experience side effects that can impact their daily lives. Common side effects include: Drowsiness; Dizziness; Fatigue; Swelling in extremities; Weight gain; Most side effects are manageable but should be discussed with a healthcare provider if Gabapentin is available in various forms and strengths, so it’s essential to follow your doctor’s dosing instructions carefully. Common side effects include dizziness and drowsiness. Always consult your healthcare provider before making any changes to your medication regimen. US Brand Names: Neurontin, Gralise, Horizant. Generic Name: Gabapentin. Gabapentin enacarbil may cause dizziness, drowsiness, or sleepiness. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert. If these side effects are especially bothersome, check with your doctor. Are there side effects I should watch for? A. Gabapentin enacarbil ( Horizant ) has been approved by the FDA for the treatment of restless legs syndrome (RLS) and postherpetic neuralgia (the pain that can linger after a bout of shingles). Gabapentin enacarbil is used for treating restless leg syndrome and postherpetic neuralgia.It is a prodrug of the anticonvulsant gabapentin, which means it is first converted to gabapentin in the body before it can have its effects. Gabapentin enacarbil available under the trade name Horizant is the only gabapentin product approved for treatment of Restless Legs Syndrome (RLS). A daily dose of 1200 mg provided no additional benefit compared with the 600 mg dose, but caused an increase in adverse reactions. While less common, the most serious side effects of Horizant are described below, along with what to do if they happen. Sleepiness, Dizziness, and Driving Impairment. Indications and Usage; Gabapentin Dosage; Gabapentin Side Effects; Interactions; Gabapentin is used to relieve excess excitement in the brain, most notably the type of excess energy or excitement that leads to restless leg syndrome or seizures. Gabapentin may cause side effects such as dizziness, drowsiness, and dizziness. and restless leg syndrome. Indications. Gabapentin is commonly prescribed for the One area of interest is the potential use of gabapentin in managing restless leg syndrome (RLS), a neurological disorder characterized by an irresistible urge to move the legs, often accompanied by unpleasant sensations. Gabapentin has common side effects and rare serious reactions. It interacts adversely with substances like alcohol, CNS depressants, and antacids.
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