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A Moderate Drug Interaction exists between gabapentin and sertraline. View detailed information regarding this drug interaction. When using Zoloft (sertraline) and gabapentin together, there are several risk factors that should be taken into consideration: 1. Central Nervous System Depression: The combined use of Zoloft and gabapentin may increase the risk of central nervous system depression, which can lead to drowsiness, dizziness, and impaired coordination. This makes side-effects more likely. If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on sertraline, as it increases the risk of side-effects, such as feeling sleepy. If you buy any medicines, check with a pharmacist that they are safe to take with sertraline. Appropriate studies have not been performed on the relationship of age to the effects of sertraline in children with . depression, panic disorder, premenstrual dysphoric disorder (PMDD), posttraumatic stress disorder (PTSD), and social anxiety disorder (SAD), and in children younger than 6 years of age with obsessive-compulsive disorder. Safety When it comes to treating conditions like anxiety, depression, and neuropathic pain, Zoloft and Gabapentin can work in tandem to provide better results. Zoloft, a selective serotonin reuptake inhibitor (SSRI), primarily addresses mood-related disorders by regulating serotonin levels in the brain. The following applies to the ingredients: Sertraline (found in Zoloft) and Gabapentin Treatment with sertraline may occasionally cause blood sodium levels to get too low, a condition known as hyponatremia, and using it with some anticonvulsants can increase that risk. Find patient medical information for Sertraline (Zoloft) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Combining Sertraline and Gabapentin may interact with other medications you’re taking. Your healthcare provider will carefully assess potential interactions and adjust your treatment plan accordingly to ensure your safety and effectiveness of treatment. Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Gabapentin (gabapentin). Common drug interactions include dizziness among females and fatigue among males. The phase IV clinical study analyzes what interactions people have when they take Zoloft and Gabapentin, and groups them by gender, age and more. Sertraline comes as a tablet and a concentrate (liquid) to take by mouth. It is usually taken once daily in the morning or evening. To treat premenstrual dysphoric disorder, sertraline is taken once a day, either every day of the month or on certain days of the month. Take sertraline at around the same time every day. Generic brands of sertraline may not be approved for the same indications or age groups as Zoloft. Sertraline side effects Common sertraline side effects. Common sertraline side effects are nausea, diarrhea, indigestion, loss of appetite, increased sweating, shaking or trembling, decreased appetite, inability to ejaculate, and decreased libido Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11] Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Gabapentin (gabapentin). Common drug interactions include malaise among females and chronic kidney disease among males. Applies to: Zoloft (sertraline) Using sertraline together with alcohol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people may also experience impairment in thinking, judgment, and motor coordination. Ways to counteract this sexual side effect of Zoloft include adding a drug that boosts dopamine, norepinephrine, and/or GABA. In your case, your doctor added gabapentin, which increased GABA activity, thereby leading to a reduction of the SSRI-induced sexual dysfunction. Both Sertraline and Gabapentin have effects on the CNS and can cause sedation, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing). In some cases, use of two or more drugs that have effects on the CNS might also increase the risk of CNS depressant effects (which could range from sedation 672 medications are known to interact with sertraline. Includes gabapentin, metoprolol, furosemide. Sertraline (Zoloft) is an oral medication used to treat major depressive disorder and other disorders. Learn about side effects, warnings, dosage, and more. Drug Interactions: A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) 10 minor drug interactions (52 brand and generic names) A total of 672 drugs are known to interact with Zoloft: One of the potential side effects of sertraline is fatigue (tiredness). But side effects of SSRIs (selective serotonin reuptake inhibitors) — including sertraline — are generally mild. If fatigue is affecting your day-to-day life, talk to your healthcare provider. While sertraline may be the cause, it’s more likely to be something else.
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