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getting an unwanted side effect. If you are not sure what to do, ask your doctor or pharmacist. If you have trouble remembering to take Gabapentin Medsurge, ask your pharmacist for help. If you take too much (overdose) Immediately telephone your doctor or Poisons Information Centre (telephone Australia 13 11 26 or New Zealand 0800 POISON or What side effects might you notice? Side Effects Recommended action Suicidal thoughts Tell your doctor immediately Confusion, trouble concentrating, memory loss Mood changes Loss of co-ordination/walking or handwriting problems, tremor Changes in vision Tell your doctor Dizziness, drowsiness, tiredness or weakness Swollen feet or legs Weight Like all medicines, pregabalin can cause side effects, although not everyone gets them. Often side effects improve as your body gets used to the new medicine. Problems with dizziness and drowsiness. This is quite common when you start taking pregabalin. Up to 1 in 3 people experience dizziness or drowsiness. This may increase the chance of you getting an unwanted side effect. If you are not sure what to do, ask your doctor or pharmacist. If you have trouble remembering to take gabapentin, ask your pharmacist for help. to 2018, gabapentin was funded with Special Authority approval and pregabalin was not funded. Since the Figure 1: Number of patients per 1,000 dispensed gabapentin and pregabalin in New Zealand from 2015 to 2020.16 N.B. In 2018, both gabapentin and pregabalin were funded without restriction; prior to 2018, gabapentin was funded with NEW ZEALAND DATA SHEET 1. PRODUCT NAME NEURONTIN 100 mg, 300 mg and 400 mg capsules NEURONTIN 600 mg and 800 mg film coated tablets 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each 100 mg capsule contains 100 mg of gabapentin. Each 300 mg capsule contains 300 mg of gabapentin. Each 400 mg capsule contains 400 mg of gabapentin. To minimise potential side effects, especially somnolence, dizziness, fatigue and ataxia, the first dose on Day 1 may be administered at bedtime. If necessary, the dose may be increased using 300 mg or 400 mg capsules three times a day up to 2400 mg/day. Dosages up to 2400 mg/day have been well tolerated in long-term open-label clinical studies. Like all medicines, gabapentin can cause side effects, although not everyone gets them. Often side effects improve as your body adjusts to the new medicine. Problems with dizziness and drowsiness. This is quite common when you start taking gabapentin. Up to 1 in 3 people experience dizziness or drowsiness. What side effects might you notice? If you notice any other effects, discuss them with your doctor or pharmacist. Gabapentin can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?) What side effects might you notice? If you notice any other effects, discuss them with your doctor or pharmacist. Gabapentin can impair your ability to do tasks such as driving or using machines. Alcohol makes this worse. Discuss your risk with your health professional. (search NZTA - Are you safe to drive?) The New Zealand Formulary. The NZF is an independent resource providing healthcare professionals with clinically validated medicines information and guidance on best practice, enabling healthcare professionals to select safe and effective medicines for individual patients. Gabapentin and pregabalin safety review CONFIDENTIAL Medicines Adverse Reactions Committee: 3 December 2020 Page 7 of 58 2.1.5 Classification In New Zealand, both gabapentin and pregabalin are prescription medicines. The Ministry’s Expert Advisory Adverse effects, e.g. weight gain and sedation, tend to be dose related and transient and often resolve within the first few weeks to months of initiating treatment. 1, 18. Cognitive effects of gabapentinoids, e.g. sedation, dizziness and euphoria. Potentiation of the effect of buprenorphine/naloxone with gabapentin or quetiapine. American Journal of Psychiatry 171(6): 691. DOI: 10.1176/appi.ajp.2014.13111526 (accessed 7 December 2020). have unwanted side effects in some people. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects. It can be difficult to tell whether side effects are the result of taking Nupentin, effects of your condition or side effects of other medicines you may be taking. For this reason vulsants can precipitate a seizure. If gabapentin is used for epilepsy and is to be discontinued, it should be done gradually over at least a week.1 Other adverse events that have been observed following the abrupt discontinuation of gabapentin include anxiety, i. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. What are the side effects of gabapentin? The side effects of gabapentin include: Nausea, vomiting, indigestion. See your doctor if these effects occur and are of concern to you. Patients over the age of 65 years have an increased chance of getting side effects. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. other activities that require you to be alert. Limit alcohol intake because it can increase these effects. Do not stop taking gabapentin without talking to your doctor first, unless you have a severe skin rash (see Side Effects). 37 Patient information leaflets (PILs) are now available from the New Zealand Formulary (NZF).
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