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Both Lyrica and gabapentin belong to a class of drugs known as anticonvulsants. The Food and Drug Administration (FDA) has approved Lyrica and gabapentin to treat the following conditions: Both Pregabalin (Lyrica) and gabapentin (Neurontin) are similar medications that treat similar conditions. But pregabalin is approved to treat more conditions than gabapentin. Both medications, though, are often used off-label. Researchers at New York University, in collaboration with colleagues at the University of Pittsburgh, have made a groundbreaking discovery in pain management, introducing a promising new medication for centralized pain that outperforms gabapentin without the risk of euphoria. The main differences between Lyrica and gabapentin are: Lyrica is a brand name for pregabalin. Gabapentin is a generic name - brands of gabapentin include Neurontin, Gralise, and Horizant. Gabapentin is not the same as pregabalin, even though they both belong to the same class of medicine, called gabapentinoids, and work similarly Similar to other anticonvulsant medicines, Neurontin may increase the risk of depression and suicidal thoughts, particularly in young adults under the age of 24. Neurontin has been associated with a discontinuation syndrome when abruptly stopped. Symptoms include anxiety, insomnia, nausea, pain, and sweating. Your doctor may prescribe you an antidepressant instead of a GABA analogue, like gabapentin, to treat pain, based on your individual health profile. According to Harvard Health, these medications include: Some people, alongside the guidance of their doctor, may decide to seek treatment without medication. Tricyclic antidepressants (TCA) such as amitriptyline and Dosulepin, and serotonin-norepinephrine reuptake inhibitors (SNRIs) such as duloxetine work to relieve pain as gabapentin alternatives. This muscle relaxant treats skeletal muscle spasms, muscle clonus, rigidity, and pain caused by multiple sclerosis. Compare Neurontin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Neurontin: Gabapentin · Oral capsule: 100 mg, 300 mg, 400 mg · Oral tablet: 600 mg, 800 mg · Oral solution: 50 milligrams per milliliter (mg/mL) Gralise: Gabapentin · Oral tablet: 300 mg, 600 mg: Horizant: Gabapentin enacarbil · ER tablet: 300 mg, 600 mg: Lyrica: Pregabalin You might want to look for safer medications if you suffer from side effects from gabapentin. I'll discuss gabapentin alternatives, precautions before switching, and side effects to watch out for in this article. If a gabapentinoid is indicated for treating neuropathic pain, however, gabapentin is often considered the first-line choice over Lyrica, due to its lower cost and similar efficacy. Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction View more. Prescription only Compare Gabapentin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Pregabalin and Gabapentin are similar medications that are used to treat the same conditions. However, Pregabalin is approved to treat more conditions compared to Gabapentin.They share a lot of similarities along with various differences in several factors. A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) (1) The first-line treatment for partial epilepsy is carbamazepine monotherapy; gabapentin monotherapy is an alternative, given its lower risk of drug-drug interactions. (2) The standard treatment for neuropathic pain associated with diabetes or post-herpetic neuralgia is a tricyclic antidepressant, Gabapentin Alternatives: Many effective substitutes exist for nerve pain relief. Natural Remedies: Options like capsaicin and turmeric can offer pain management. Prescription Options: Medications such as Pregabalin and Amitriptyline may help. Download the free Optum Perks Discount Card to save up to 80% on some prescription medications. Summary. If you’re looking for gabapentin alternatives, prescription medication options are available that may be effective. Some OTC substitutes and natural remedies also can help, but they usually work best when you take them along with medical care.
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