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Sleep paralysis (SP) occurs when rapid eye movement (REM)-based atonia perseverates into wakefulness. 1 Most individuals with SP also experience dream activity during the conscious paralysis that is vivid, multisensorial, and often negatively valenced. The combination of atonia and waking nightmares makes SP a very unpleasant experience for Chronic neuropathic pain (NP) is debilitating and impacts sleep health and quality of life. Treatment with gabapentinoids (GBs) has been shown to reduce pain, but its effects on sleep health have not been systematically evaluated. The objective of this systematic review and meta-analysis was to asse This study is the first to systematically assess the clinical value of gabapentin for the treatment of sleep disorders. We found that regardless the type of sleep outcomes, gabapentin displayed stable treatment efficacy for sleep disturbance in patients with medical illness. However, when an average Well, to be fair, gabapentin does its job pretty well, especially if you have damaged nerves/neurological conditions. Pregabalin (lyrica) is a much "cleaner" version of Gabapentin and causes far fewer side effects. I know tons of people that take one or the other and have no problems at all. I do think that adverse side effects are Restless legs syndrome is treated with gabapentin or dopamine agonists, depending on the severity. Narcolepsy is characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, and Gabapentin is safe and effective in improving the sleep quality of patients with sensory nervous-system diseases. Due to the limitations of sample size and types of diseases in the current study, the field needs multicenter, large-sample, and high-quality RCTs for further validation in the future. Gabapentin is considered highly effective for the treatment of insomnia for a few reasons. First and foremost, it improves sleep quality by reducing spontaneous arousal in the brain. It also increases total sleep time thanks to fewer awakenings and its ability to help individuals go to sleep faster. Sleep paralysis is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Xyrem, and have Narcolepsy. Like baclofen, some studies have shown that gabapentin might be of interest in alcohol dependence management [2]. In this context, baclofen is linked to sleep apnea syndrome [3, 4], aggravating sleep-disordered breathing by depressing central ventilatory drive and/or increasing upper airway obstruction. Discussion. This study revealed that without consideration of the type of sleep outcomes, gabapentin was significantly superior to placebos for the treatment for sleep disorders secondary to RLS, neuropathic pain, alcohol dependence, hot flashes in menopause, fibromyalgia, phantom limb pain, HIV-associated sensory neuropathies, and bipolar disorder. One trial showed that using pregabalin alone and using it with an opioid pain reliever can depress breathing function. The other trial showed gabapentin alone increased pauses in breathing during sleep. We study how severe was Sleep paralysis, when it was recovered, drug effectiveness, race, and more among people who take Gabapentin. This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly. Isolated sleep paralysis is experienced at least once by up to 40% of the general population, whereas recurrence is less frequent. Isolated sleep paralysis can be accompanied by very intense and vivid hallucinations. Sleep paralysis represents a dissociated state, with persistence of REM atonia into wakefulness. Gabapentin and sleep. Most studies show that gabapentin improves slow wave sleep (“deep sleep”) and total sleep time. Two small studies showed that gabapentin may help people with primary insomnia and occasional sleep disturbance improve total sleep time and wakefulness in the morning. We investigated the acute effects of gabapentin (GABA) on sleep breathing in older men without sleep apnea. A double-blind, randomized, placebo-controlled cross-over pilot study using a bedtime dose of gabapentin 300 mg was conducted in eight non-obese older men. Nighttime wheezes and daytime haze collide in a pharmaceutical tango, where gabapentin and sleep apnea lock arms, challenging both patients and doctors to find the perfect rhythm for restful slumber. Gabapentin (a GABA analog enhancing GABA synthesis) and structurally related pregabalin, known as gabapentinoids, are both used in the treatment of epilepsy and neuropathic pain. The main adverse effects reported with gabapentinoids are sleepiness, dizziness, headache, nausea, and vomiting. Clinical studies have revealed that gabapentin could improve the objective and subjective outcomes of sleep disturbance in patient with medical illness (13 – 37). Gabapentin Enacarbil (GEn) or XP13512 is a prodrug of gabapentin, used as an anticonvulsant and for pain relief in postherpetic neuralgia. Gabapentin and pregabalin are FDA-approved for a variety of conditions, including in breathing during sleep. The three observational studies at one academic medical center I've had sleep paralysis before. My dad gets it, too, but he doesn't take gabapentin. I've had it before gabapentin, and I've had it a lot on phenibut which I used to take as a sleep aid and it would give me very vivid, lucid dreams, but some would be sleep paralysis. I read a lot into sleep paralysis.
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