No, gabapentin does not directly cause high blood sugar levels. Current research indicates that there is no significant link between gabapentin use and elevated glucose levels. The medication primarily affects neurotransmitter activity and does not alter insulin function directly. Summary: Blood glucose abnormal is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes. Gabapentin has been associated with both hypoglycemia and hyperglycemia in different patient cases. The drug's interaction with GABA receptors and voltage-gated calcium channels may influence insulin secretion, leading to these varying effects on blood sugar levels. The SmPC of gabapentin mentions blood glucose fluctuations in diabetic patients as a potential adverse drug reaction with unknown frequency [1]. The current observation describes the association between gabapentin and severe hypoglycaemia in diabetic and non-diabetic patients. Reports When considering the use of Gabapentin for diabetics, several potential benefits arise: Pain Relief: Many diabetics suffer from neuropathic pain due to nerve damage caused by high blood sugar levels. Gabapentin can significantly reduce this pain. Improved Sleep: Chronic pain often disrupts sleep patterns. By alleviating discomfort, Gabapentin Gabapentin has not been reported to raise blood sugar, however it would be best to consult a pharmacist/doc who would have prescribed the med. Take care, be well & safe! Votes: +0 Hypothetically, gabapentin-induced GABA A receptor activation could stimulate insulin release resulting in hypoglycaemia. Alternatively, direct binding to the alpha 2 -delta 2 receptor of the voltage-gated calcium channels could also provide a pharmacological explanation. Sometimes, high levels of blood sugar are temporary and settle when you stop taking the medication. But certain medications can increase the risk of developing Type 2 diabetes. If your medications cause high blood sugars, you may need to closely check your levels and work with your healthcare team to adjust your medications. While there is evidence suggesting that gabapentin can potentially raise blood sugar levels in some individuals, particularly those with pre-existing diabetes, there are also multiple reports of gabapentin causing hypoglycemia. askyourpharm.com High blood sugar is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Depression. Gabapentin is in a class of medications called anticonvulsants. What are the brand names of gabapentin? Gabapentin is available as both a brand name product and a generic product (chemically the same, usually lower cost than the brand name product). Brand names of gabapentin include Horizant®, Gralise® and Neurontin®. The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gabapentin) and Gabapentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. If gabapentin causes any fluctuations in glucose levels, modification of drug therapy is warranted to correct the abnormalities and an association with gabapentin may go unnoticed. In addition, the number of patients with diabetes receiving gabapentin may not be known at a specific point in time. The short answer is: yes, it is possible, though not very common, for gabapentin to raise your blood sugar. Studies have shown that approximately 1.2% of patients treated with gabapentin may experience hyperglycemia (high blood sugar) compared to 0.4% with a placebo. yes..High Blood Sugar rare side effects of Neurontin.. please consult with your health care provider as soon as possible.. good luck. Postmarketing research of gabapentin has shown fluctuation of blood glucose levels. Ask your doctor to evaluate your blood glucose levels for hypoglycemia. He/she might want to adjust your dose of gabapentin, or send you to a dietician to establish a special diet to control the low blood sugar if your glucose is not dropping too severely. Drugs That May Cause Hyperglycemia (High Blood Sugar) Abacavir (Ziagen®) Abacavir + lamivudine,zidovudine (Trizivir®) Abacavir + dolutegravir + lamivudine (Triumeq®) Abiraterone (Zytiga®) Acetazolamide (Diamox®) Acitretin (Soriatane®) Aletinib (Alecensa®) Albuterol (Ventolin®, Proventil®) Albuterol + ipratropium (Combivent®) One-time overdoses of gabapentin can result in symptoms such as sleepiness, loss of coordination, and diarrhea. However, if the human liquid form containing xylitol is overdosed, it can lead to severe drops in blood sugar levels and liver damage, which are potentially life-threatening. Objective: A possible case of gabapentin-induced mild hyperglycemia is reported. Case Summary: A 63-year-old Caucasian gentleman was treated in a pharmacist-run pharmacotherapy clinic for type 2
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