Gabapentin is usually used to manage chronic pain, especially nerve-related pain. It is also used (primarily in cats) to relieve anxiety associated with veterinary procedures, travel, and other fear-generating situations. Gabapentin can also be used as an additional medication in seizure management. Gabapentin is an anticonvulsant drug effective in humans to control neuropathic pain. In veterinary medicine, is extra-label used in combination with other treatments to control seizures when other drugs are not effective, when drugs are toxic, or for neuropathic pain treatment and anxiety. One of the most commonly cited uses of gabapentin in veterinary medicine is for treating acute post-operative pain. 5 Considering the mechanism of action of gabapentin and its impact on pain signaling, it is unlikely that gabapentin will be an effective analgesic in this context. In fact, a panel of experts (World Small Animal Veterinary Association Global Pain Council) recommends the perioperative use of gabapentin as an adjunctive treatment to prevent postsurgical pain, or in circumstances with limited availability of drugs. 5 In cats, gabapentin has excellent bioavailability (approximately 89%) after oral Kukanich B, Cohen RL. Pharmacokinetics of oral gabapentin in greyhound dogs. Vet J 2011;187(1):133-135. Siao KT, Pypendop BH, Ilkiw JE. Pharmacokinetics of gabapentin in cats. Am J Vet Res 2010;71(7):817-821. Lorenz ND, Comerford EJ, Iff I. Long-term use of gabapentin for musculoskeletal disease and trauma in three cats. J Feline Med Surg 2013 Gabapentin is a human medication, and its use in veterinary medicine is “off-label,” meaning it is not FDA-approved for pets. But gabapentin can be prescribed to help with pain, seizures, and anxiety in dogs. The use of gabapentin in veterinary medicine has increased dramatically in the last several years. Despite its popularity, there is a narrow indication of its use in veterinary patients. There is also growing evidence that gabapentin is being diverted for recreational drug use, sometimes with fatal consequences. As a result, Traditionally, gabapentin has been utilized in veterinary medicine for management of neuropathic pain and as an anticonvulsant.4 However, in human medicine it has also been used to treat patients with social anxiety and panic disorder.5 In the last several years veterinary behaviorists have used gabapentin as an adjunctive therapy for anxiety It is most effective when used with an opioid or NSAID, but is also effective when used with gabapentin. Because of its use in chronic pain management, amantadine is ideal when introduced during the weaning of ketamine in a postoperative setting. 1. Gabapentin Gabapentin (brand names: Neurontin®, Aclonium®, Equipax®, Gantin®, Gabarone®, Gralise®, Neurostil®, Progresse®) is an anti-seizure and pain medication that is used with other medications to treat seizures and chronic pain, primarily nerve pain, in dogs and cats. * The anti-seizure drug is widely used in human and veterinary medicine to manage pain. * Gabapentin is approved only for human use, but extralabel use in veterinary medicine is legal and common. * There are concerns in human and veterinary medicine alike that the drug is overprescribed. In veterinary medicine, Gabapentin is used “off-label” and in conjunction with other meds to prevent neuropathic pain and manage pets with seizures. Keep reading to learn everything you need to know about Gabapentin for dogs. This medicine is authoried for use in human patients and is used by vets under the prescribing cascade. The medicine is not authoried by the eterinary edicines irectorate V, an eecutive agency of the epartment for nvironment, ood and ural airs efra, for use in dogscatspets. our vet can eplain the Gabapentin. is most commonly used in veterinary medicine to relieve chronic. pain and in some pets, to reduce fear and anxiety associated with veterinary. appointments. Gabapentin may be used alone or in combination with other drugs. Gabapentin is available as capsules, tablets and as an oral solution. GENERAL DESCRIPTION: Gabapentin In veterinary medicine, is extra-label used in combination with other treatments to control seizures when other drugs are no longer effective or become toxic or for neuropathic pain treatment and anxiety. This review aimed to clarify gabapentin use and pharmacokinetic aspects to promote conscious use in dogs, cats, and horses. * The anti-seizure drug is widely used in human and veterinary medicine to manage pain. * Gabapentin is approved only for human use, but extralabel use in veterinary medicine is legal and common. * There are concerns in human and veterinary medicine alike that the drug is overprescribed.
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