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Background Pregabalin is an anticonvulsive, analgesic and anxiolytic medication. The typical side effects include dizziness, somnolence and weight gain. Few studies or case reports have demonstrated psychiatric side effects resulting from its use. Case presentation We present a patient who suffered visual hallucinations and agitation associated with an increase in pregabalin dose, resolving Objectives: Visual hallucinations (VHs) and pain are common non-motor symptoms in Parkinson disease (PD). Although dopaminergic dysfunction has traditionally been considered as the principal cause of these symptoms, the detail mechanisms are still unclear. A 65-year-old woman with no psychiatric history developed visual hallucinations while taking gabapentin five times daily. Her hallucinations resolved after discontinuation of gabapentin and have remained absent after 1 year of follow-up. Gabapentin-induced hallucinations, both visual and auditory, are significant adverse effects that require careful management. Dose adjustment and discontinuation are effective strategies, while alternative treatments may be considered in specific cases. Pregabalin is used in generalized anxiety disorder, as it is thought to act on alpha-2 delta subunits of voltage-dependent calcium channels as a neurotransmitter release inhibitor 75 and is potentially efficacious in social anxiety disorders at certain dosages. 76 Blurry vision and diplopia are some of the more common effects secondary to Acute visual hallucinations should be considered in the clinical spectrum of very rare side effects of pregabalin use, especially at higher doses. Tapered discontinuation of the medication can improve and resolve symptoms. Keywords: Pregabalin, Visual hallucinations, Side effect, Adverse reaction. Background A 65-year-old woman developed visual hallucinations during the off-label treatment with gabapentin for neuropathic pain; she was taking the gabapentin dosage at an inappropriate frequency. The woman presented with complaints of visual hallucinations, daytime sleepiness and fatigue. In this case series, the authors describe four patients with either visual or musical hallucinations associated with sensory impairment who were successfully treated with gabapentin. Sensory impairment hallucinations, such as visual hallucinations with visual loss, may not respond to traditional treatments such as antipsychotics. In elderly patients, visual hallucinations may be caused by dementia, delirium, drug-induced states or primary psychiatric disorders. Based on 3 characteristics (visual loss, clearly formed recurrent visual hallucinations, and insight into the unreal nature of the hallucinations), our patient received a diagnosis of Charles Bonnet syndrome. Much of the research into whether or not gabapentin can cause hallucinations is inconclusive. However, it can be said that some people have reported experiencing hallucinations while taking the medication, so it is important to be aware of the potential risks associated with taking gabapentin. In this case series, the authors describe four patients with either visual or musical hallucinations associated with sensory impairment who were successfully treated with gabapentin. View Explore millions of resources from scholarly journals, books, newspapers, videos and more, on the ProQuest Platform. Purpose: A case of probable gabapentin-induced visual hallucinations in a patient with no psychiatric history is reported. Summary: A 65-year-old white woman with no history of psychiatric A 70-year-old man Footnote 1 experienced visual hallucinations while receiving gabapentin. The man had underlying chronic kidney disease (on haemodialysis), cataracts and cerebrovascular disease, specifically old bilateral occipital and right frontal lobe infarcts. He had been receiving gabapentin [indication, dosage and route not stated]. Two The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. In this article, we report four cases of hallucinations associated with sensory impairment, three visual hallucinations and one musical hallucination, that responded to gabapentin. To our knowledge, this is the only case of musical hallucinations successfully treated with gabapentin. Here, we report a patient who developed psychotic and depressive symptoms after gabapentin use. A 50-year-old female patient had complaints of feeling sad and fearful, reluctance, crying, out loud self-talk, visual hallucinations, decreased sleep, and loss of appetite for the last two weeks. Because she was distressed, gabapentin, 100 mg h.s., was begun, with some reduction of the visual hallucinations. The dosage was eventually increased to 400 mg, with resolution of the visual hallucinations. She remained free of visual hallucinations for 6 months and then suddenly lost vision in her other eye. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. The medications most often associated with visual hallucinations include those used to treat high blood pressure, erectile dysfunction, psychiatric and mood disorders, movement disorders like Parkinson disease, and some antibiotics, Dr. Fraunfelder said.
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