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Does gabapentin interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal In general, some studies have shown that gabapentin is an antiepileptic drug with a low profile of interaction with other drugs. 68, 69 Specifically, a general review stated that gabapentin lacks interactions with hepatic enzymes, plasma proteins and other drugs; these factors make gabapentin suitable for elderly patients suffering from hepatic Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Specific Drugs: Gabapentin can interact with other prescription medications such as losartan, ethacrynic acid, caffeine, phenytoin, mefloquine, magnesium oxide, cimetidine, naproxen, sevelamer, and morphine. These interactions can lead to altered drug levels or an increased risk of side effects. Some medicines may affect how gabapentin works or increase the chance of you having side effects. Antacids can reduce the amount of gabapentin that the body takes in so it does not work as well. To stop this happening, if you need to take an antacid, take it at least 2 hours before or after your dose of gabapentin. Gabapentin (Neurontin, Gralise, Horizant) is a medicine used to treat partial seizures, nerve pain from shingles and restless leg syndrome. It works on the chemical messengers in your brain and nerves. Gabapentin is from a group of medicines called anticonvulsants. What medications should be avoided with gabapentin? Medications that should generally be avoided with gabapentin include opioids, benzodiazepines, and certain antidepressants. These combinations can lead to increased sedation and other serious side effects. Always consult your healthcare provider for personalized advice. How do drug Taking gabapentin together with other medications can lead to drug interactions. Some of the drugs that can potentially interact with gabapentin include: Naproxen. Studies suggest that naproxen (aleve) increases the amount of gabapentin absorbed in the body. It is safe to take gabapentin and other medications that have been prescribed or ordered by your doctor. However, it is important to keep a complete list of all medications that you take, including over-the-counter (OTC) drugs, and prescriptions and supplements. People should review this list with their health care provider periodically. Gabapentin should not be mixed with any other illicit drugs, alcohol, or certain prescription medications like hydrocodone and morphine. If you’re considering taking an over-the-counter medication while on gabapentin, discuss it with your doctor before making a decision. Gabapentin is a drug used to treat certain types of seizures, postherpetic neuralgia, and other nerve pain. It is also used to treat restless legs syndrome. Gabapentin is usually well tolerated, but like all medications, it can interact with other drugs and substances. The main types are: Drug-drug interaction.This is when a medication reacts with one or more other drugs. For example, taking a cough medicine (antitussive) and a drug to help you sleep (sedative In short, the most common over-the-counter (OTC) pain relievers, such as acetaminophen (Tylenol) and ibuprofen (Advil), are generally considered safe to take with gabapentin. Are There Other Drugs That Can Be Taken Instead of Gabapentin? Pregabalin is Gabapentin alternatives for epilepsy, nerve pain, and anxiety. Other drugs for nerve pain include topiramate, baclofen, tricyclic antidepressants such as amitriptyline and Dosulepin, and serotonin-norepinephrine reuptake inhibitors such as duloxetine. Antiepileptic drugs (AEDs) have been associated with an increased risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Pooled analyses of 199 placebo-controlled clinical studies involving the use of 11 different AEDs showed that patients receiving AEDs had approximately twice the risk of suicidal thinking or Alternative prescription medications. If you’re looking for gabapentin alternatives, several prescription medications can help manage nerve pain, fibromyalgia, and anxiety. These include: Pregabalin: Doctors often prescribe pregabalin (Lyrica) as a substitute for gabapentin for nerve pain and fibromyalgia. Gabapentin, a medication primarily used to treat seizures and nerve pain, is generally considered safe when used as directed. However, like many medications, it can interact negatively with other substances, leading to unwanted side effects or reduced efficacy.
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