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The prevalence of depression as a side effect of gabapentin use is difficult to pinpoint precisely, as it can vary depending on the patient population and study methodology. However, it’s estimated that between 1% and 10% of patients taking gabapentin may experience depression as a side effect. There is insufficient evidence to support the use of gabapentin for bipolar disorder, major depressive disorder (MDD), or posttraumatic stress disorder (PTSD). Further research is needed to determine its effectiveness in these conditions. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects. 4. Bottom Line. Gabapentin is an anticonvulsant with pain Gabapentin has been associated with various psychiatric side effects, including depression. Patients taking this medication have reported significant personality changes and heightened feelings of depression, aggression, and suicidal ideation. Gabapentin is primarily an anticonvulsant medication, yet its association with psychiatric side effects, including depression, has garnered attention. While classified as serious but uncommon, reports indicate that depression can be exacerbated in individuals with a history of psychological issues. Gabapentin can affect mood and may cause depressive symptoms, though this is considered a rare side effect. While it is primarily used to treat seizures and nerve pain, some individuals have reported experiencing feelings of sadness or worsening depression during treatment. Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Watch for breathing issues Gabapentin isn’t usually used to treat anxiety alone. More often, it’s given to ease anxiety symptoms for someone who also has depression or bipolar disorder. (Anxiety is commonly comorbid with In the present case, we discuss the side-effects of gabapentin, used as part of the multimodal treatment approach of painful spinal degenerative disease. The patient stated that he had noticed personality changes after gabapentin was initiated, and that he had become more depressed, frustrated, and aggressive. Depression is a serious, yet uncommon, side effect of using gabapentin. It can either cause depression or make existing cases of depression worse. Individuals have a higher risk of developing depression as a side effect if they already have a history of a psychological disorder. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. The Perfect Storm: Factors Influencing Gabapentin’s Mental Side Effects. Now, you might be wondering, “Why do some people experience these side effects while others don’t?” Well, it’s not as simple as flipping a coin. Several factors can influence how gabapentin affects your mental health. Dosage and duration of use play a significant It took almost 2 weeks after that before those mining explosions stopped. For me, I have to stay on gabapentin at this high dose and accept side effects. If you can do without gabapentin and you don't like side effects, do that. I do sleep better these last 5 years since I started gabapentin. Some patients find that activities like yoga or meditation can help balance out some of the psychological effects of gabapentin. In some cases, considering alternative medications may be necessary. If the psychological side effects of gabapentin are proving too challenging, your doctor might suggest trying a different medication. Side effects of gabapentin. Common side effects of gabapentin include: drowsiness or dizziness; headache or blurred vision; nausea, vomiting, diarrhea, constipation; dry mouth; weight gain; swelling of the hands, feet, or ankles; back or joint pain; flulike symptoms such as fever or body aches. Rare but serious side effects. Rare but serious While there is no direct link between Gabapentin and depression, it's important to understand that Gabapentin is not free of side effects. The most common side effects of therapeutic doses of Gabapentin include drowsiness, somnolence, dizziness, movement disorders, diarrhea, and weight gain. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Gabapentin can help control seizures as well as nerve pain from shingles. It may sometimes cause side effects, especially if you misuse it. Learn more.
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