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Neurontin (gabapentin) is associated with memory loss in a dose dependent fashion, meaning the higher doses you take, the more chance there is of having some sort of memory loss, or cognitive impairment. Mental impairment, confusion and memory loss are recognized side effects. Some people use the term fuzzy thinking to describe the brain impact. Sleepiness and dizziness are quite common complications of both drugs. Your doctor should have warned you about the dangers of driving while taking either medicine. After a literature review, we were unsure of the duration the drugs would require to cause the side effects of cognitive impairment or dementia. We conducted a preliminary analysis, including gabapentin or pregabalin exposure period of 30 days and 90 days. Does gabapentin cause memory loss? Some people taking gabapentin, mostly those with chronic kidney disease, have reported problems with short-term memory loss. However, it’s not clear if gabapentin is actually responsible for these brain function issues. One study found that gabapentin alone did not affect memory or cause memory impairment or Yes, memory loss is a potential side effect of Gabapentin. While not experienced by everyone, some individuals may notice difficulties with memory or concentration while taking Gabapentin for pain and symptom management. Side effects of gabapentin. Common side effects of gabapentin include: drowsiness or dizziness; headache or blurred vision; nausea, vomiting, diarrhea, constipation; dry mouth; weight gain; swelling of the hands, feet, or ankles; back or joint pain; flulike symptoms such as fever or body aches. Rare but serious side effects. Rare but serious Gabapentin use has been associated with memory loss and cognitive decline. Studies suggest that the risk of dementia may be higher in patients treated with gabapentin. It is important for patients and healthcare providers to be aware of the potential cognitive side effects of gabapentin. Fortunately, memory loss and other side effects associated with gabapentin are not considered permanent and should resolve upon discontinuation of therapy or with a dose decrease. Some of the most common Gabapentin long-term side effects include: Memory loss: Long-term gabapentin use has been linked to problems with memory and difficulty concentrating. Consult your physician if you have concerns about gabapentin and memory loss. Studies have shown that gabapentin alone does not cause memory loss or impairment when used for long-term treatment. However, some patients may experience brain fog or slight confusion as potential side effects. However, gabapentin seems to be different from the traditional antiseizure drugs, and the exact mechanism(s) through which gabapentin exerts both its clinical and potential side effects is still unknown. One hypothesis includes binding to the alpha2-delta subunit of the voltage-dependent calcium channel (Rose and Kam, 2002). Considering that Some studies show that gabapentin may have effects on your memory. But we need more research on this topic to be sure. Still, older adults are more at risk of memory issues and medication side effects in general. A 2022 study looked at 480 adults aged 65 and older who were taking gabapentin. Memory loss caused by Gabapentin may improve or resolve after stopping the medication, but not everyone will experience a complete recovery. Strategies such as using memory aids, practicing good sleep hygiene, exercising regularly, maintaining a healthy diet, and considering cognitive rehabilitation therapy can help manage memory issues. Memory loss, minor memory impairment can happen to those who take gabapentin. In the package insert for the drug, it mentions that mild memory loss was a side effect that certain participants got, although it wasn't that common. About 2% of those in clinical trials had some form of cognitive impairment on the drug. Memory loss and confusion is a known side effect of Gabapentin. I found a doc who agreed with the memory issue and walked me through the step down necessary to get off. Wishing you well. Explore gabapentin's effects on mental function, memory, and cognition. Learn about managing side effects and balancing therapeutic benefits with potential risks. When compared with the nondrug condition, both medications resulted in significantly worse performance on tests of verbal memory and motor speed, and participants reported a high incidence of sedative effects. Frequently reported side-effects for gabapentin included fatigue, unsteadiness, and dizziness. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. And as a consequence, memory and attention and sleepiness are common side effects of these medications,” says Aatif M. Husain, M.D., a professor of neurology and the division chief of epilepsy, sleep and neurophysiology in the department of neurology at the Duke University School of Medicine in Durham, North Carolina. Gabapentin, a medication commonly prescribed for nerve pain and seizures, has been linked to potential cognitive side effects, including memory loss. While its therapeutic benefits are well-documented, some individuals report experiencing forgetfulness or difficulty concentrating during its use.
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