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ScriptWorks is a California-based compounding pharmacy. Prescription medications are shipped only to California addresses. Before compounding or dispensing prescription medications, ScriptWorks requires each patient to provide a current patient-specific prescription from a licensed healthcare provider. This cream combines the actions of gabapentin, an anticonvulsant that is also used to relieve neuropathic pain; ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain; and lidocaine, a local anesthetic that numbs the treated area. Nociceptive pain (pain typically caused by injury or inflammation): The active treatment was 10% ketoprofen, 2% baclofen, 2% cyclobenzaprine and 2% lidocaine. Neuropathic pain (pain due to nerve injury): The active treatment was 10% ketamine, 6% gabapentin, 0.2% clonidine, and 2% lidocaine. Intranasal ketamine solution (10%) and cream-form gabapentin (6%), ketoprofen (10%), lidocaine 5%, and ketamine (10%) have helped relieve this pain with no adverse effects. Complex Regional Pain Syndrome (CRPS) The Gabapentin 10%/Ketoprofen 15%/Lidocaine HCl 5%/Menthol 5% Topical Cream is a specially compounded semisolid preparation intended for localized treatment of neuropathic pain, inflammatory conditions, and associated symptoms. Gabapentin (Neurontin, cyclohexaneacetic acid, C 9 H 17 NO 2, MW 171.24) occurs as a white to off-white, crystalline solid that is freely soluble in water and in alkaline and acidic solutions. A 2% aqueous solution has a pH of 6.5 to 8.0. Gabapentin is an anticonvulsant that is structurally related to gamma-aminobutyric acid. Gabapentin topical creams and gels have been shown to be effective for treating chronic neuropathic pain. Neuropathic pain is pain coming from damaged nerves. It differs from pain messages carried along healthy nerves from damaged tissue that can come from a burn or a cut. Chronic NeP can markedly diminish both quality of life and daily function. Pain reduction is the main goal of treatment, but improving sleep, daily function, and quality-of-life are also important. 1 First-line medications include oral amitriptyline, gabapentin and pregabalin. Keto Gaba Lido Cream is a pain-relieving cream that contains a combination of Ketoprofen, Gabapentin, and Lidocaine. It is used to treat neuropathic pain and provide relief from inflammation and pain. The Gabapentin 10%/Ketoprofen 5% Transdermal Gel is a compounded medication designed for topical application. Gabapentin is an anticonvulsant that is commonly used to treat neuropathic pain, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can be used to alleviate pain and inflammation. Gabapentin 4-10% AMPA-Na Channel Blocker Lidocaine 2-5% AMPA-Na Channel Blocker Diclofenac 2-10% Anti-inflammatory Ibuprofen 10-20% Anti-inflammatory Ketoprofen 5-20% Anti-inflammatory Naproxen 10-20% Anti-inflammatory Piroxicam 2-4% Anti-inflammatory Gabapentin/Ketoprofen/Lidocaine Transdermal Gel is a compounded medication that combines three active ingredients, Gabapentin, Ketoprofen, and Lidocaine, at specific concentrations to manage pain, inflammation, and nerve-related issues locally through application on the skin. This formulation is a compounded topical cream containing Amitriptyline 5%, Cyclobenzaprine 5%, Gabapentin 5%, Ketoprofen 10%, Lidocaine 5%, and Tramadol 5%. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. It has amantadine 6%, gabapentin 3%, cyclobenzaprine 2%, lidocaine 5%, clonidine 0.2%, diclofenac 3%, and nifedipine 0.2% in one bottle and I mix it with calcipotriene-betamethisone DP ointment. It actually works really well. Ketoprofen - This is a non-steroidal anti-inflammatory drug (NSAID) that works to reduce inflammation and pain. Ketoprofen is similar to ibuprofen and naproxen but is more effective topically than either of those agents. An advantage of topical ketoprofen is that high tissue concentrations are achieved without high systemic concentrations. This compounded formulation of Baclofen 2%/Ketoprofen 10%/Lidocaine 5%/Gabapentin 5% Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. Background: The use of compounded topical pain creams has increased dramatically, yet their effectiveness has not been well evaluated. Objective: To determine the efficacy of compounded creams for chronic pain. A new topical cream with gabapentin 6 percent, ketoprofen 10 percent, lidocaine 5 percent, and ketamine 10 percent was prescribed in addition to an oral mucosal topical agent containing gabapentin 10 percent in Orabase. The researchers think there was a tiny difference favoring the pain creams because they contained two substances—lidocaine and prescription non-steroidal anti-inflammatory drugs, particularly ketoprofen and diclofenac—that were shown in earlier randomized trials to be effective topically. Gabapentin taken orally has been used for treatment of partial seizures,55 postherpetic neuralgia,56 migraine headaches,57 and other pain syndromes.58,59 Fortunately, gabapentin has a low profile of adverse effects and few interactions with other medi-cations because it requires high doses to achieve neuropathic pain relief.
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