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Neuropathy is usually considered a symptom or complication of another underlying condition. Thus, the most effective treatment is the one that targets the underlying cause. It's important to note that once neuropathy develops, it cannot be reversed or cured. I read all the summaries of the lastest studies and there is currently nothing better than exercise for many conditions. I would not take gabapentin or any of the other common drugs that are used for neuropathy UNLESS you are really suffereng from pain. These drugs have only a small effect on numbness or tingling. What other drugs will affect gabapentin? Taking gabapentin with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your current medicines. Many drugs A trial compared four drugs for neuropathy with unknown cause, but none was very effective or safe. Nortriptyline and duloxetine seemed to work better than pregabalin and mexiletine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Gabapentin (Neurontin) is a cousin to pregabalin, but it’s a bit cheaper. It’s not FDA-approved to treat diabetic neuropathy, but it’s typically used off-label for this purpose. It’s often recommended as another first-choice option. Duloxetine (Cymbalta) is another medication that’s FDA-approved to treat diabetic neuropathy. There are three options: Tricyclic antidepressants, such as amitriptyline (Elavil), doxepin (Sinequan), and nortriptyline (Pamelor). These drugs are prescribed for pain at doses lower than are effective for depression. Serotonin–norepinephrine reuptake inhibitors (SNRIs), such as duloxetine (Cymbalta) and venlafaxine (Effexor). Other drugs: Neuropathic pain (mainly diabetic peripheral neuropathy and postherpetic neuralgia), the anticonvulsants gabapentin, pregabalin, and oxcarbazepine produced small improvements in Pregabalin (Lyrica), gabapentin (Neurontin), amitriptyline (except in older adults), or duloxetine (Cymbalta) should be used as first-line treatment for painful diabetic peripheral neuropathy. A 1 Some people with neuropathic pain turn to familiar over-the-counter painkillers like acetaminophen, aspirin, ibuprofen, and topical medicines like capsaicin cream. While these drugs might help Are There Other Drugs That Can Be Taken Instead of Gabapentin? Pregabalin is Gabapentin alternatives for epilepsy, nerve pain, and anxiety. Other drugs for nerve pain include topiramate, baclofen, tricyclic antidepressants such as amitriptyline and Dosulepin, and serotonin-norepinephrine reuptake inhibitors such as duloxetine. For instance, taking an anticonvulsant, such as gabapentin or pregabalin, alongside a TCA antidepressant could be more effective than taking either type of drug alone. Compare risks and benefits of common medications used for Peripheral Neuropathy. Find the most popular drugs, view ratings and user reviews. A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) However, because of their side effects, many doctors only turn to these drugs when other treatments haven't worked. Opioid painkillers can cause constipation, stomach upset, and sedation. Canadian Agency for Drugs in Technology and Health (CADTH) 2018 review found a lack of clear evidence to support gabapentin use in fibromyalgia and neuropathic pain conditions other than painful diabetic neuropathy and post herpetic neuralgia15 He said the anti-seizure medication Neurontin (gabapentin) has the fewest side effects. Lyrica (pregabalin, another anti-seizure medication) comes next, and the antidepressant Cymbalta (duloxetine, a serotonin and norepinephrine reuptake inhibitor) has the most. Compare Gabapentin head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
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