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Gabapentin, an anticonvulsant sold under the brand name Neurontin, is used to treat seizures and neuropathic pain. It is typically the first course of action, and most often prescribed to patients with diabetic neuropathy or postherpetic neuralgia. Gabapentin’s effects on the body are multifaceted, but in the context of weight loss, two key aspects are worth noting: Appetite suppression: Gabapentin has been shown to decrease appetite in some individuals, potentially leading to weight loss. Gabapentin is approved for use in children 3 years of age and older for certain indications٫ such as partial seizures. The dosage for pediatric patients is determined based on their weight and specific condition. The origins of Gabapentin can be dated back to the 1970s in Japan, where it was created and used as an anti-spasmodic—muscle relaxant. For years, it was used for this specific purpose until experts found that the tablet could successfully treat other conditions, such as epilepsy, nerve pain, shingles, and more, without posing severe risks to patients. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system. It is not used for routine pain caused by minor injuries or arthritis. Gabapentin is an anticonvulsant. The cause of weight gain with gabapentin is likely due to increased appetite. You may be hungry more often. In some cases, weight gain may be due to fluid retention, another side effect of gabapentin. Another possible cause is not getting enough exercise if gabapentin is causing fatigue. Some ways to avoid weight gain include: Gabapentin (Neurontin, Gralise, Horizant) is a medicine used to help manage certain epileptic seizures. It also is used to relieve pain for some conditions, such as shingles. Dizziness and drowsiness are common side effects of gabapentin. Some other possible side effects include weight gain and trouble with movement. Similar weight change was noted with exenatide 10, 15, and 20 μg. The weight loss with exenatide weekly dosing was 0.9 kg, and with daily dosing it was 1.3 kg (P value for difference = .7). Weight loss with GLP-1 agonists used < 3 months was 0.3 kg, 3–6 months was 1.3 kg, and > 6 months was 0.9 kg. Weight gain is not considered a common side effect of gabapentin. In clinical trials, only about 2% of people reported weight gain with its use. In people who do gain weight while on gabapentin, a research study showed a weight gain of about 5.5 pounds after 1.5 months of use. However, weight gain was a common side effect associated with gabapentin (7.5% of patients) while weight loss was linked to topiramate (22.5% of patients) . 3.2.2. Expert opinion: weight-centric approach weakness or loss of strength; weight gain; Managing side effects Nemire RE, Haley K (1995) "Weight gain and gabapentin therapy." Ann Pharmacother, 29, p. 1048. 14 The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. I experience loss of appetite while taking Gabapentin. At first I would see triggers such as a photo of food or some food smelled tasty and think, "boy, I'd like that" but immediately after I'd think-"but I'm not hungry". A total of 1.8 to 2.9 percent of adolescents and adults in some clinical trials with Neurontin experienced weight gain. In one study with children aged 3 to 12 years, 3.4 percent gained weight while taking Neurontin, compared with 0.8 percent taking a placebo. Summary: Weight loss is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fluoxetine, and have Schizophrenia.
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