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Along with its needed effects, gabapentin (the active ingredient contained in Neurontin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common side effects Medications are a common reason for swollen ankles and feet, also called pedal edema. Amlodipine (Norvasc), gabapentin (Neurontin, Horizant, Gralise), and pregabalin (Lyrica) can cause puffy legs and ankles. Birth control pills, certain over-the-counter pain medications, and steroids are a few other culprits. Summary: High blood pressure is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Rheumatoid arthritis. Can gabapentin cause high blood pressure? Yes, abruptly stopping gabapentin can lead to rebound hypertension , a withdrawal symptom. Additionally, while not a direct cause, the cardiovascular risks associated with long-term use can indirectly affect blood pressure. Gabapentin is associated with a risk of dependence and withdrawal. Abrupt discontinuation of the drug may result in symptoms similar to those of benzodiazepine or alcohol withdrawal and may include: Hypertension (high blood pressure). Sweating. Confusion. Incoherent speech. Impaired ability to pay attention. Nausea. Pain. Insomnia. Restlessness Experts believe gabapentin may cause brain cells to produce more of a chemical called GABA, which reduces abnormal electrical activity of brain cells. In people experiencing nerve pain after having had shingles, gabapentin is thought to change the way pain signals are sent through the body and brain. Gabapentin is in a class of medications called anticonvulsants. What are the brand names of gabapentin? Gabapentin is available as both a brand name product and a generic product (chemically the same, usually lower cost than the brand name product). Brand names of gabapentin include Horizant®, Gralise® and Neurontin®. Research on rats has shown that gabapentin may lower blood pressure in those with high blood pressure Although gabapentin can cause several adverse reactions, many people experience no serious But that doesn’t mean one can suffer high blood pressure when taking gabapentin. Here’s what happens. When an individual withdraws abruptly from gabapentin and uses the drug for nerve pain regulation, there’s a chance the pain could return. Then, unilateral microinjection of gabapentin into the NTS before and after N(ω)-nitro-L-arginine methyl ester (L-NAME) treatment whether to change blood pressure and heart rate. Results: Unilateral microinjection of gabapentin into the NTS produced prominent dose-related depressor and bradycardic effects in SHR rats. The cardiovascular Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system. It is not used for routine pain caused by minor injuries or arthritis. Gabapentin is an anticonvulsant. More rarely, gabapentin can cause fluid buildup (edema), weight gain, and vision problems. It can also cause diarrhea. More serious (but rare) side effects include suicidal thoughts or behavior, and mood changes in children. Not everyone who takes gabapentin will experience changes in blood pressure. However, certain factors may increase your risk, including: * Age: Older adults may be more susceptible to blood pressure changes. * Existing blood pressure issues: If you already have high or low blood pressure, gabapentin may exacerbate these issues. Gabapentin is fairly safe when you use it correctly. It does come with some possible side effects, though. People who misuse this drug are also at risk of additional side effects. Gabapentin is Background Gabapentin and pregabalin are commonly prescribed medications to treat pain in patients with diabetic neuropathy. Gabapentin and pregabalin can cause fluid retention, which is hypothesized to be associated with cardiovascular diseases. However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown. This study aims to Like all medicines, gabapentin can cause side effects, although not everyone gets them. These common side effects of gabapentin may happen in more than 1 in 100 people. They're usually mild and go away by themselves. There are things you can do to help cope with them: As your body gets used to gabapentin, these side effects should wear off. Oral and intravenous gabapentin can markedly attenuate blood pressure (BP) in hypertensive rats. The nucleus tractus solitarii (NTS) is the primary integrative center for cardiovascular control and other autonomic functions in the central nervous system. Research suggests that gabapentin can lower blood pressure by reducing the body’s production of certain hormones that can increase blood pressure. It may also help to relax blood vessels, making it easier for blood to flow through them. Yes, it can cause High Blood Pressure (hypertension) Cardiovascular side effects including hypertension have been reported to occur in more than one percent of patients taking gabapentin. Read more at: Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults, treating the pain of post herpetic neuralgia. Gabapentin belongs to a class of drugs known as anti-seizure drugs. Take gabapentin by mouth as directed by your doctor, usually once a day with the evening meal.
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